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高胆固醇血症兔血小板中前列腺素的合成

Synthesis of prostaglandins in platelets of hypercholesterolemic rabbits.

作者信息

Srivastava K C

出版信息

Lipids. 1975 Jan;10(1):57-9. doi: 10.1007/BF02532196.

DOI:10.1007/BF02532196
PMID:1123976
Abstract

As a continuation of previous studies on the synthesis of prostaglandins in platelets of human venous blood, the present communication describes the synthesis of prostaglandins in experimental hypercholesterolemia induced in rabbits by dietary means. In such a condition, high serum level of cholesterol did not change the rate of prostaglandin synthesis.

摘要

作为先前关于人静脉血血小板中前列腺素合成研究的延续，本报告描述了通过饮食方法在兔身上诱导的实验性高胆固醇血症中前列腺素的合成。在这种情况下，高血清胆固醇水平并未改变前列腺素的合成速率。

相似文献

1
Synthesis of prostaglandins in platelets of hypercholesterolemic rabbits.高胆固醇血症兔血小板中前列腺素的合成
Lipids. 1975 Jan;10(1):57-9. doi: 10.1007/BF02532196.
2
Morphological and kinetic abnormalities of platelets in hypercholesterolemic rabbits.高胆固醇血症兔血小板的形态学和动力学异常
Atherosclerosis. 1988 Nov;74(1-2):23-32. doi: 10.1016/0021-9150(88)90187-6.
3
Thromboxane B2 biosynthesis and phospholipids hydrolysis in platelets from hypercholesterolemic rabbits.高胆固醇血症兔血小板中血栓素B2的生物合成及磷脂水解
Lipids. 1981 Jan;16(1):37-42. doi: 10.1007/BF02534919.
4
Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: role in development of hypercholesterolemic atherosclerosis.高胆固醇血症血小板中鞘氨醇-1-磷酸的释放增强：在高胆固醇血症动脉粥样硬化发展中的作用。
Prostaglandins Leukot Essent Fatty Acids. 2008 Jun;78(6):383-90. doi: 10.1016/j.plefa.2008.04.010. Epub 2008 Jun 20.
5
Thromboxane synthesis in hypercholesterolemic platelets--on the mechanism of increased thromboxane synthesis.高胆固醇血症血小板中血栓素的合成——关于血栓素合成增加的机制
Hokkaido Igaku Zasshi. 1983 May;58(3):292-309.
6
Platelet hypersensitivity in cholesterol-fed rabbits: enhancement of thromboxane A2-dependent and thrombin-induced, thromboxane A2-independent platelet responses.胆固醇喂养兔的血小板超敏反应：血栓素A2依赖性和凝血酶诱导的、血栓素A2非依赖性血小板反应的增强。
Atherosclerosis. 1991 May;88(1):77-86. doi: 10.1016/0021-9150(91)90259-6.
7
Collagen-induced calcium influx is enhanced in platelets from hypercholesterolemic rabbits.
Thromb Res. 1985 Oct 1;40(1):59-68. doi: 10.1016/0049-3848(85)90350-0.
8
Increased thromboxane B2 biosynthesis in platelets.血小板中血栓素B2生物合成增加。
Lipids. 1982 Sep;17(9):577-84. doi: 10.1007/BF02535362.
9
Diet-induced hypercholesterolemia inhibits the recovery of prostacyclin production by injured rabbit aorta.饮食诱导的高胆固醇血症会抑制受伤兔主动脉中前列环素生成的恢复。
Am J Pathol. 1982 May;107(2):186-90.
10
Relationship between serum cholesterol and thromboxane B2 levels and atherosclerotic lesions in rabbits fed a high cholesterol diet.高胆固醇饮食喂养的兔子血清胆固醇与血栓素B2水平及动脉粥样硬化病变之间的关系。
Int Angiol. 1990 Oct-Dec;9(4):256-8.

本文引用的文献

1
The synthesis of prostaglandins in human platelets.人类血小板中前列腺素的合成。
Lipids. 1972 Apr;7(4):246-50. doi: 10.1007/BF02533221.
2
Extraction of prostaglandins from human blood.从人体血液中提取前列腺素。
Nature. 1971 Oct 1;233(5318):336-7. doi: 10.1038/233336b0.
3
Use of lysed human platelets to study prostaglandin E2 production.使用裂解的人血小板来研究前列腺素E2的产生。
Prostaglandins. 1974 Feb 25;5(4):387-95. doi: 10.1016/s0090-6980(74)80122-x.
4
Stability of prostaglandin E compounds in solution.前列腺素E类化合物在溶液中的稳定性
Lipids. 1973 Oct;8(10):592-4. doi: 10.1007/BF02532717.
5
Extraction of prostaglandins E1, E2 and E3 from human seminal plasma.
Lipids. 1973 Jul;8(7):431-3. doi: 10.1007/BF02531721.
6
Synthesis of prostaglandins (PGE, PGF, PGA and PGB) in human platelets.人血小板中前列腺素（PGE、PGF、PGA和PGB）的合成。
Lipids. 1972 Dec;7(12):762-5. doi: 10.1007/BF02533242.
7
Platelet aggregation induced by arachidonic acid is accompanied by release of potential inflammatory mediators distinct from PGE2 and PGF2.花生四烯酸诱导的血小板聚集伴随着不同于前列腺素E2和前列腺素F2的潜在炎症介质的释放。
Nat New Biol. 1973 Jul 25;244(134):114-6. doi: 10.1038/newbio244114a0.
8
Prostaglandin E1 and platelets.
Biomedicine. 1973 Mar;18(2):95-102.
9
Platelet aggregation. I. Regulation by cyclic AMP and prostaglandin E1.血小板聚集。I. 环磷酸腺苷和前列腺素E1的调节作用
Biochem Biophys Res Commun. 1969 Sep 10;36(6):965-72. doi: 10.1016/0006-291x(69)90298-8.
10
Arachidonic acid-induced human platelet aggregation and prostaglandin formation.花生四烯酸诱导的人血小板聚集和前列腺素形成。
Prostaglandins. 1973 Dec;4(6):863-75. doi: 10.1016/0090-6980(73)90121-4.