Guerzider V, Creuzot-Garcher C, Bielefeld P, Bron A
Service d'Ophtalmologie, Hôpital Général, Dijon.
J Fr Ophtalmol. 2001 Jan;24(1):69-72.
Cogan's syndrome is an inflammatory disease that is characterized by ocular inflammation (typically interstitial keratitis) and is associated with Ménière-like vestibuloauditory dysfunction. Ocular inflammation usually resolves after several weeks or months but deafness is often irreversible. We report on a case of Cogan's syndrome in a 23-year-old woman who initially presented with bilateral anterior uveitis, an unusual clinical feature for this disease. We discuss the clinical aspects, the pathogenic mechanisms, the laboratory investigations, the differential diagnosis, and the treatment of Cogan's syndrome.
科根综合征是一种炎症性疾病，其特征为眼部炎症（通常为间质性角膜炎），并伴有梅尼埃样前庭听觉功能障碍。眼部炎症通常在数周或数月后消退，但耳聋往往不可逆转。我们报告了一例23岁女性的科根综合征病例，该患者最初表现为双侧前葡萄膜炎，这是该疾病不常见的临床特征。我们讨论了科根综合征的临床特点、发病机制、实验室检查、鉴别诊断及治疗。
