Schlötterer C
Institut für Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria.
Heredity (Edinb). 2000 Dec;85(Pt 6):610-6. doi: 10.1046/j.1365-2540.2000.00797.x.
The neo-sex chromosomes of Drosophila americana americana were formed by a centric fusion between the autosomal element B and the X chromosome. Previous work has shown that the neo-Y chromosome is not degenerated genetically and that there is no evidence for genetic differentiation between neo-X and neo-Y chromosomes at the sequence level. To further address the genetic differentiation between the neo-sex chromosomes, microsatellites mapping to the neo-sex chromosome of D. a. americana were isolated. Microsatellite analysis indicated a highly significant differentiation between D. a. americana and D. a. texana as well as between the neo-X and neo-Y chromosomes in D. a. americana. Nevertheless, levels of variability were similar among the neo-sex chromosomes, indicating a very recent origin.
美洲果蝇的新性染色体是由常染色体元件B和X染色体之间的着丝粒融合形成的。先前的研究表明，新Y染色体在遗传上并未退化，并且在序列水平上没有证据表明新X染色体和新Y染色体之间存在遗传分化。为了进一步研究新性染色体之间的遗传分化，分离了定位到美洲果蝇新性染色体上的微卫星。微卫星分析表明，美洲果蝇和德克萨斯果蝇之间以及美洲果蝇的新X染色体和新Y染色体之间存在高度显著的分化。然而，新性染色体之间的变异水平相似，表明其起源非常近。
