Walpole R, Olday J, Haetzman M, Drummond G B, Doyle E
Department of Anaesthesia, Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK.
Paediatr Anaesth. 2001 Mar;11(2):157-60. doi: 10.1046/j.1460-9592.2001.00629.x.
We studied the respiratory effects of the administration of either 5% halothane or 8% sevoflurane in 70% nitrous oxide (N2O) for 5 min in 21 boys aged 1-5 years. A similar degree of ventilatory depression was noted with both agents. Minute volume fell by approximately 50% as a result of a reduction in tidal volume despite an increase in respiratory rate.
我们对21名1至5岁的男孩进行了研究，在70%的氧化亚氮（N2O）中给予5%的氟烷或8%的七氟醚5分钟，观察其对呼吸的影响。两种药物均观察到相似程度的通气抑制。尽管呼吸频率增加，但由于潮气量减少，分钟通气量下降了约50%。
