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Fetal varicella-herpes zoster syndrome in early pregnancy: ultrasonographic and morphological correlation.

作者信息

Petignat P, Vial Y, Laurini R, Hohlfeld P

机构信息

Department of Gynecology and Obstetrics, CHUV, Lausanne, Switzerland.

出版信息

Prenat Diagn. 2001 Feb;21(2):121-4. doi: 10.1002/1097-0223(200102)21:2<121::aid-pd996>3.0.co;2-p.

DOI:10.1002/1097-0223(200102)21:2<121::aid-pd996>3.0.co;2-p
PMID:11241539
Abstract

We report a case of an intrauterine fetal infection by the varicella-herpes zoster virus following maternal varicella at 17 weeks' amenorrhea. Prenatal diagnosis of fetal infection was confirmed by serology and fetal damage by ultrasonography. Autopsy of the fetus showed multiorgan manifestation with disseminated foci of necrosis and microcalcifications, encephalitis and unilateral segmental skin scarring with an underlying hypoplastic fixed lower limb. The placenta showed a multifocal chronic villitis with multinucleated giant cells. The lesions included segmental anomalies and multiorgan damage.

摘要

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