Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, USA.
BJOG. 2011 Sep;118(10):1155-62. doi: 10.1111/j.1471-0528.2011.02983.x. Epub 2011 May 18.
Congenital varicella syndrome, maternal varicella-zoster virus pneumonia and neonatal varicella infection are associated with serious fetomaternal morbidity and, not infrequently, mortality. Vaccination against varicella-zoster virus can prevent the disease, and outbreak control limits the exposure of pregnant women to the infectious agent. Maternal varicella-zoster immunoglobulin administration before rash development, with or without antiviral medication, can modify the progression of the disease.
先天性水痘综合征、母体水痘带状疱疹病毒肺炎和新生儿水痘感染与严重的母婴发病率有关，而且往往导致死亡。接种水痘带状疱疹病毒疫苗可以预防这种疾病，爆发控制也可以限制孕妇接触病原体。在皮疹出现之前，无论是否使用抗病毒药物，给予母体水痘带状疱疹免疫球蛋白可以改变疾病的进程。
