Löser C
I Medical Department, Christian-Albrechts-University, Kiel, Germany.
Br J Nutr. 2000 Nov;84 Suppl 1:S55-8. doi: 10.1017/s0007114500002257.
Polyamines are highly regulated polycations which are essentially involved in cell growth and differentiation. Polyamines in food significantly contribute to the polyamine body pool. Dietary polyamines exert various direct and indirect trophic effects on the rat's immature intestine and play an important role during intestinal maturation. Human milk and that of other mammalians contain relatively high levels of polyamines which are essential luminal growth and maturation factors. The polyamines spermidine and spermine as well as their diamine precursor putrescine are ubiquitous normal constituents of all prokaryotic and eukaryotic cells and are essentially involved in various processes of cell growth and differentiation (Pegg & McCann, 1982; Tabor & Tabor, 1984; Seiler, 1990).
多胺是受到高度调控的聚阳离子，它们在细胞生长和分化过程中发挥着重要作用。食物中的多胺对多胺体内储备有显著贡献。膳食多胺对大鼠未成熟肠道具有多种直接和间接的营养作用，并在肠道成熟过程中发挥重要作用。人乳和其他哺乳动物的乳汁中含有相对较高水平的多胺，这些多胺是重要的管腔生长和成熟因子。多胺亚精胺和精胺及其二胺前体腐胺是所有原核和真核细胞普遍存在的正常成分，并在细胞生长和分化的各种过程中发挥着重要作用（佩格和麦肯，1982年；泰伯和泰伯，1984年；塞勒，1990年）。
