Nedz'ved' M K, Fridman M V
Minsk State Medical Institute, City Bureau of Pathology, 220798, Minsk.
Arkh Patol. 2001 Jan-Feb;63(1):38-40.
One case of chronic herpetic meningoencepalitis complicated by a rare my costs of the central nervous system (CNS) and generalised viral infection is described. Cladosporiosis is considered as a lesion resulting from a immunosuppression due to chronic herpetic involvement of CNS. Morphologically this mycosis is manifested by the presence of spors and septic micelium among cells of productive inflammation an inside of giant multinuclear cells in affected areas. Viral nature of the encephalomyelitis is documented by presence of typical intranuclear inclusions and detection of herpetic antigen by means of fluorescent antibodies.
本文描述了一例慢性疱疹性脑膜脑炎合并罕见的中枢神经系统霉菌感染及全身性病毒感染的病例。枝孢菌病被认为是由于中枢神经系统慢性疱疹感染导致免疫抑制而引起的病变。从形态学上看,这种霉菌病表现为在受累区域的增生性炎症细胞以及巨大多核细胞内部存在孢子和败育菌丝体。脑脊髓炎的病毒性质通过典型的核内包涵体的存在以及借助荧光抗体检测疱疹抗原得以证实。