Uter W, Schwanitz H J, Pfahlberg A, Gefeller O
Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Germany.
Dermatology. 2001;202(1):4-8. doi: 10.1159/000051576.
Score concepts have been suggested for the standardised diagnosis of atopic dermatitis, incorporating various anamnestic and clinical minor criteria of atopy, including the 'Erlangen Score', developed in the hospital-based setting of a dermatitis clinic.
To evaluate the properties of this score in the context of a population-based epidemiological study.
The association between relevant atopic criteria and previous or current flexural eczema was evaluated in 2,352 hairdressing apprentices.
The association was not as strong as in the patient-based studies, comparing the respective odds ratios. Accordingly, the discriminating power of the Erlangen Score was poor, resulting in low sensitivity (55.7%) and specificity (73.8%) for, e.g., 8 points as cutpoint.
While the score appears useful to summarise minor criteria, the individual relevance of its point values should not be overestimated in view of a low positive predictive value in a population (compared to a clinical) setting.
已提出评分概念用于特应性皮炎的标准化诊断，纳入了各种特应性的既往史和临床次要标准，包括在一家皮炎门诊的医院环境中制定的“埃尔朗根评分”。
在一项基于人群的流行病学研究背景下评估该评分的特性。
在2352名美发学徒中评估相关特应性标准与既往或当前屈侧湿疹之间的关联。
比较各自的优势比，该关联不如基于患者的研究中那么强。因此，埃尔朗根评分的鉴别能力较差，例如以8分为切点时，敏感性低（55.7%），特异性低（73.8%）。
虽然该评分似乎有助于总结次要标准，但鉴于在人群（与临床相比）环境中阳性预测值较低，其分值的个体相关性不应被高估。
