Department of Cutaneous Allergy, St John's Institute of Dermatology, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.
Contact Dermatitis. 2010 Mar;62(3):177-81. doi: 10.1111/j.1600-0536.2009.01696.x.
Allergic contact dermatitis is common in hairdressers because of their exposure to chemicals used in hair dyes and permanent wave solutions. Atopic individuals are known to have a higher prevalence of leaving the profession due to morbidity associated with hand eczema.
To assess which chemicals are responsible for allergic contact dermatitis in hairdressers and whether the prevalence is the same according to atopy status.
A total of 729 hairdressers who had been patch tested were retrospectively identified. Allergic reactions to relevant allergens from the extended European baseline series and hairdressing series were analysed against history of atopic eczema.
Of the total, 29.9% of patients had a current or past history of atopic eczema. The most frequent positive allergens from the European baseline series were nickel sulfate (32.1%) and p-phenylenediamine (19.0%) and from the hairdressing series were glyceryl monothioglycolate (21.4%) and ammonium persulfate (10.6%). There was no significant difference between people with or without a history of atopic eczema, except for fragrance mix I and nickel sulfate.
We present findings from the largest cohort of hairdressers patch tested from a single centre. It is necessary to patch test hairdressers with dermatitis, regardless of a history of atopy. Strategies to reduce prevalence of allergic contact dermatitis are required.
由于美发师接触染发剂和烫发剂中的化学物质，因此他们常患有过敏性接触性皮炎。已知特应性个体由于手部湿疹相关的发病率，更有可能因患病而离开该职业。
评估哪些化学物质会导致美发师发生过敏性接触性皮炎，以及特应性状态是否会影响其患病率。
回顾性确定了 729 名接受斑贴试验的美发师。根据特应性皮炎史，分析了扩展的欧洲基准系列和美发系列中相关变应原的过敏反应。
在所有患者中，29.9%的患者目前或过去有特应性湿疹史。欧洲基准系列中最常见的阳性变应原是硫酸镍（32.1%）和对苯二胺（19.0%），美发系列中最常见的阳性变应原是甘油单硫代甘油酸（21.4%）和过硫酸铵（10.6%）。有或没有特应性湿疹史的人群之间除了香料混合物 I 和硫酸镍外，没有其他显著差异。
我们报告了来自单一中心的最大美发师斑贴试验队列的结果。有必要对患有皮炎的美发师进行斑贴试验，无论是否有特应性。需要采取策略来降低过敏性接触性皮炎的患病率。
