Körner H, Söreide J A, Pedersen E J, Bru T, Söndenaa K, Vatten L
Department of Surgery, Rogaland Central Hospital, Stavanger, Norway.
Dig Surg. 2001;18(1):61-6. doi: 10.1159/000050099.
BACKGROUND/AIM OF THE STUDY: During the past 50 years, a decrease in incidence of appendicitis has been reported. The various studies were retrospective and based on different data sources. In the present study, we analyze prospectively the incidence of acute appendicitis during a 10-year period in a well defined population of 265,000.
Prospective registration of all operations performed in patients with suspected acute appendicitis in the catchment area of a single institution. The diagnosis of acute appendicitis was based on histology in all cases. The annual incidence of acute appendicitis was calculated with regard to nonperforated and perforated acute appendicitis.
Between 1989 and 1998, 2,861 patients underwent surgery for suspected acute appendicitis. In 2,232 (78%) patients, acute appendicitis was confirmed histologically. Mean annual incidence was 84/100,000 (95% confidence interval 80 to 88/100,000). Crude incidence remained stable during the study period, with the exception of a significant increase in 1991 followed by a significant decrease the next year. Nonperforated acute appendicitis showed a different incidence pattern as compared to perforated acute appendicitis.
In our prospective study, the incidence of acute appendicitis remained stable in our well-defined study population during the study period of 10 years. This is in contrast to the majority of studies during the last decades.
研究背景/目的:在过去50年中,已有报告称阑尾炎发病率有所下降。各项研究均为回顾性研究,且基于不同的数据来源。在本研究中,我们对一个明确界定的265,000人群在10年期间急性阑尾炎的发病率进行了前瞻性分析。
对单个机构服务区域内疑似急性阑尾炎患者进行的所有手术进行前瞻性登记。所有病例的急性阑尾炎诊断均基于组织学检查。计算非穿孔性和穿孔性急性阑尾炎的年发病率。
1989年至1998年期间,2861例患者因疑似急性阑尾炎接受了手术。其中2232例(78%)患者经组织学确诊为急性阑尾炎。年平均发病率为84/10万(95%置信区间80至88/10万)。在研究期间,粗发病率保持稳定,但1991年显著上升,次年又显著下降。与穿孔性急性阑尾炎相比,非穿孔性急性阑尾炎呈现出不同的发病率模式。
在我们的前瞻性研究中,在为期10年的研究期间,我们明确界定的研究人群中急性阑尾炎的发病率保持稳定。这与过去几十年的大多数研究结果相反。