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急性阑尾炎:手术治疗趋势—一项超过 80 万患者的基于人群研究。

Acute Appendicitis: Trends in Surgical Treatment—A Population-Based Study of Over 800 000 Patients.

机构信息

Department of Surgery, Klinikum rechts der Isar, School of Medicine, Technical University of MunichMünchner Studienzentrum, Klinikum rechts der Isar, School of Medicine,Technical University ofMunichDepartment of Health Care Management, Institute of Technology and Management, TechnischeUniversität Berlin.

出版信息

Dtsch Arztebl Int. 2021 Apr 9;118(14):244-249. doi: 10.3238/arztebl.m2021.0118.

Abstract

BACKGROUND

Appendectomy is the gold standard for treatment of acute appendicitis. However, recent studies favor primary antibiotic therapy. The aim of this observational study was to explore changes in the numbers of operations for acute appendicitis in the period 2010-2017, paying special attention to disease severity.

METHODS

Data from diagnosis-related group statistics were used to analyze the trends, mortality, and complication rates in the surgical treatment of appendicitis in Germany between 2010 and 2017. All cases of appendectomy after a diagnosis of appendicitis were included.

RESULTS

Altogether, 865 688 inpatient cases were analyzed. The number of appendectomies went down by 9,8%, from 113 614 in 2010 to 102 464 in 2017, while the incidence fell from 139/100 000 in 2010 to 123/100 000 in 2017 (standardized by age group). This decrease is due to the lower number of operations for uncomplicated appendicitis (79 906 in 2017 versus 93 135 in 2010). Hospital mortality decreased both in patients who underwent surgical treatment of complicated appendicitis (0.62% in 2010 versus 0.42% in 2017) and in those with a complicated clinical course (5.4% in 2010 versus 3.4% in 2017).

CONCLUSION

Decisions on the treatment of acute appendicitis in German hospitals follow the current trend towards non-surgical management in selected patients. At the same time, the care of acute appendicitis has improved with regard to overall hospital morbidity and hospital mortality.

摘要

背景

阑尾切除术是治疗急性阑尾炎的金标准。然而,最近的研究倾向于采用原发性抗生素治疗。本观察性研究的目的是探讨 2010 年至 2017 年间急性阑尾炎手术数量的变化,特别关注疾病的严重程度。

方法

使用诊断相关组统计数据来分析德国 2010 年至 2017 年阑尾炎手术治疗的趋势、死亡率和并发症发生率。所有诊断为阑尾炎后进行阑尾切除术的病例均包括在内。

结果

共分析了 865688 例住院病例。阑尾切除术的数量下降了 9.8%,从 2010 年的 113614 例降至 2017 年的 102464 例,而发病率从 2010 年的每 10 万人 139 例降至 2017 年的每 10 万人 123 例(按年龄组标准化)。这种下降是由于单纯性阑尾炎手术数量减少(2017 年为 79906 例,而 2010 年为 93135 例)。接受复杂阑尾炎手术治疗的患者(2010 年为 0.62%,而 2017 年为 0.42%)和临床过程复杂的患者(2010 年为 5.4%,而 2017 年为 3.4%)的医院死亡率均有所下降。

结论

德国医院治疗急性阑尾炎的决策遵循当前在选定患者中采用非手术治疗的趋势。与此同时,急性阑尾炎的治疗在总体医院发病率和医院死亡率方面得到了改善。

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