Hussey L C, Hynan L, Leeper B
College of Nursing and Health Professions, University of North Carolina at Charlotte, Charlotte, NC, USA.
Am J Crit Care. 2001 Mar;10(2):112-6.
Differences between men and women in complication rates after cardiac surgery have been reported. The rate of one of the most severe postoperative complications, sternal wound infection, has not been compared between the sexes.
To compare the frequencies of 21 risk factors for sternal wound infection between men and women.
Records of 306 patients who had cardiac surgery between 1989 and 1999 at 3 different hospitals in the southwestern and southeastern United States were reviewed for 21 risk factors. Of the 306 patients, 115 (25 women and 90 men) had experienced a sternal wound infection and 191 randomly selected patients (52 women and 139 men) had not.
Three risk factors occurred at significantly different rates in men and women. Smoking and use of a single internal mammary artery for grafting were more common in men than women. Women were older than men at the time of cardiac surgery. Logistic regression analyses showed that the 3 dichotomous risk factors (use of single internal mammary artery for grafting, smoking, age > 70 years) that univariate analysis indicated were significantly related to sex could also be used to predict infection group.
This study contributes to the awareness of the possible differences between men and women in the risk of sternal wound infection developing after cardiac surgery. Although 3 risk factors occurred at significantly different rates in men and women, further research is needed to determine the effects that these differences in risk factors may have on the occurrence of sternal wound infection in men and women.
已有报道称心脏手术后男性和女性的并发症发生率存在差异。然而，最严重的术后并发症之一——胸骨伤口感染的发生率在两性之间尚未进行比较。
比较男性和女性发生胸骨伤口感染的21个风险因素的频率。
回顾了1989年至1999年在美国西南部和东南部3家不同医院接受心脏手术的306例患者的记录，以分析21个风险因素。在这306例患者中，115例（25例女性和90例男性）发生了胸骨伤口感染，另外随机选择了191例患者（52例女性和139例男性）未发生感染。
有3个风险因素在男性和女性中的发生率存在显著差异。吸烟和使用单支胸廓内动脉进行移植在男性中比女性更常见。女性在进行心脏手术时的年龄比男性大。逻辑回归分析表明，单因素分析显示与性别显著相关的3个二分风险因素（使用单支胸廓内动脉进行移植、吸烟、年龄>70岁）也可用于预测感染组。
本研究有助于提高人们对心脏手术后男性和女性发生胸骨伤口感染风险可能存在差异的认识。尽管有3个风险因素在男性和女性中的发生率存在显著差异，但仍需要进一步研究来确定这些风险因素的差异可能对男性和女性胸骨伤口感染发生率产生的影响。
