Passler M A, Riggs R V
Healthsouth Rehabilitation Hospital, Dothan, AL, USA.
Arch Phys Med Rehabil. 2001 Mar;82(3):311-5. doi: 10.1053/apmr.2001.20831.
To assess the effects of multidisciplinary rehabilitation interventions and use of bromocriptine on outcome in patients with traumatic brain injury-vegetative state (TBI-VS).
Retrospective review of clinical cases.
Free-standing rehabilitation hospital; Acute and extended rehabilitation hospital.
Five consecutive TBI-VS patients, as well as 33 TBI-VS patients and 37 traumatic brain injury-minimally conscious state (TBI-MCS) patients reported in the literature.
Bromocriptine administration, systematic neuropsychologic testing, sensory stimulation, and traditional comprehensive rehabilitation with physical therapy, occupational therapy, and speech therapy.
Disability Rating Scale (DRS) at 1, 3, 6, and 12 months postinjury and FIM instrument scores at 1 month and 12 months postinjury, Coma Recovery Scale, and Barry Rehabilitation Inpatient Screening of Cognition.
The 5 TBI-VS patients emerged from a VS into a MCS and regained functional status. Their recovery of physical and cognitive functioning, as rated by the DRS, was greater than previously reported in the literature for patients in a VS or MCS at 3, 6, and 12 months postinjury.
Bromocriptine administration, systematic neuropsychologic testing, sensory stimulation, a comprehensive rehabilitation program, or a combination of these treatments may enhance functional recovery in this TBI-VS patient group. Further systematic study to quantify the contribution of these variables and to reproduce this data in a larger patient population should be performed.
评估多学科康复干预及使用溴隐亭对创伤性脑损伤-植物状态（TBI-VS）患者预后的影响。
临床病例回顾性研究。
独立康复医院；急性和长期康复医院。
连续5例TBI-VS患者，以及文献报道的33例TBI-VS患者和37例创伤性脑损伤-最小意识状态（TBI-MCS）患者。
给予溴隐亭、系统神经心理学测试、感觉刺激，以及物理治疗、职业治疗和言语治疗等传统综合康复治疗。
伤后1、3、6和12个月时的残疾评定量表（DRS）评分，伤后1个月和12个月时的FIM工具评分、昏迷恢复量表，以及巴里康复住院认知筛查量表。
5例TBI-VS患者从植物状态转为最小意识状态并恢复了功能状态。根据DRS评定，他们在伤后3、6和12个月时身体和认知功能的恢复情况优于文献中此前报道的处于植物状态或最小意识状态的患者。
给予溴隐亭、系统神经心理学测试、感觉刺激、综合康复计划或这些治疗方法的联合应用可能会促进该TBI-VS患者群体的功能恢复。应开展进一步的系统研究，以量化这些变量的作用，并在更大的患者群体中重现该数据。
