Schmidt K, Schöll A
Z Kinderheilkd. 1975;119(1):37-45.
From 1969 to 1973 171 peroral intestinal biopsies were carried out at the Children's Hospital Tübingen using the Crosby-Kugler capsule and the Watson intestinal biopsy capsule of paediatric size. The dissecting microscope findings were compared with the histological findings. The former correlated in stage II and III, according to the Shmerling scale, with the histological findings. Findings under the dissecting microscope, stage I, did not correlate in all cases with the histological findings. It is supposed that this results from either an inaccurate orientation or from inadequate sectioning. The plane of sectioning must be parallel to the villi. If the plane of sectioning is not parallel to the villi, the slender villi under the dissecting microscope look like plump villi when examined histologically. It is supposed that this results in a greater number of plump villi and a smaller number of slender villi in the histological findings compared with the dissecting microscope findings. The correspondence of slender villi examined under the dissecting microscope and those which are histologically examined in about 25 to 100%.
1969年至1973年期间，图宾根儿童医院使用克罗斯比 - 库格勒胶囊和儿科尺寸的沃森肠道活检胶囊进行了171次经口肠道活检。将解剖显微镜下的发现与组织学结果进行了比较。根据施梅林分级，解剖显微镜下的发现与组织学结果在II期和III期相关。解剖显微镜下I期的发现并非在所有情况下都与组织学结果相关。据推测，这要么是由于定位不准确，要么是由于切片不充分所致。切片平面必须与绒毛平行。如果切片平面与绒毛不平行，那么在解剖显微镜下细长的绒毛在组织学检查时看起来就像丰满的绒毛。据推测，这导致组织学结果中丰满绒毛的数量比解剖显微镜下的发现更多，而细长绒毛的数量更少。解剖显微镜下检查的细长绒毛与组织学检查的细长绒毛的符合率约为25%至100%。
