Janssen-Heijnen M L, Coebergh J W, Klinkhamer P J, Schipper R M, Splinter T A, Mooi W J
Eindhoven Cancer Registry, Comprehensive Cancer Center South, Eindhoven, The Netherlands.
Epidemiology. 2001 Mar;12(2):256-8. doi: 10.1097/00001648-200103000-00020.
We studied possible explanations for the deteriorating survival for adenocarcinoma of the lung between 1975 and 1994 in relation with trends in incidence. The proportion of adenocarcinoma among men has been increasing since 1975 and for those born after 1920, while survival has decreased since 1975 and for those born since 1930. Among women, both the proportion of adenocarcinoma and survival have remained more or less constant. The rising incidence and the decreasing survival may both be related to changes in tobacco use, the increased use of low-tar filter cigarettes since the 1960s being the most likely candidate.
我们研究了1975年至1994年间肺腺癌生存率恶化与发病率趋势相关的可能解释。自1975年以来，男性中腺癌的比例一直在上升，对于1920年以后出生的男性也是如此，而自1975年以来生存率下降，对于1930年以后出生的男性也是如此。在女性中，腺癌比例和生存率都或多或少保持稳定。发病率上升和生存率下降可能都与烟草使用的变化有关，自20世纪60年代以来低焦油过滤嘴香烟使用增加是最有可能的原因。
