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Mutational and epigenetic evidence for independent pathways for lung adenocarcinomas arising in smokers and never smokers.吸烟者和从不吸烟者发生的肺腺癌独立途径的突变和表观遗传学证据。
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2
Patterns of lung cancer mortality in 23 countries: application of the age-period-cohort model.23个国家的肺癌死亡率模式：年龄-时期-队列模型的应用
BMC Public Health. 2005 Mar 5;5:22. doi: 10.1186/1471-2458-5-22.
3
Regression models for relative survival.相对生存的回归模型。
Stat Med. 2004 Jan 15;23(1):51-64. doi: 10.1002/sim.1597.
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The relative survival rate: a statistical methodology.相对生存率：一种统计方法。
Natl Cancer Inst Monogr. 1961 Sep;6:101-21.
5
Relationship of different histological lung tumour groups to tobacco smoking.不同组织学类型的肺肿瘤组与吸烟的关系。
Br J Cancer. 1961 Mar;15(1):51-3. doi: 10.1038/bjc.1961.7.
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The significance of cell type in relation to the aetiology of lung cancer.细胞类型与肺癌病因学的关系
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The changing epidemiology of lung cancer in Europe.欧洲肺癌流行病学的变化
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8
Adenocarcinoma of the lung is strongly associated with cigarette smoking: further evidence from a prospective study of women.肺癌腺癌与吸烟密切相关：一项女性前瞻性研究的进一步证据。
Am J Epidemiol. 2002 Dec 15;156(12):1114-22. doi: 10.1093/aje/kwf153.
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Loss of heterozygosity and the smoking index increase with decrease in differentiation of lung adenocarcinomas: etiologic implications.肺腺癌分化程度降低时杂合性缺失及吸烟指数增加：病因学意义
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Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.肺腺癌的激光捕获显微切割及微阵列表达分析揭示了与吸烟和预后相关的分子谱。
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瑞典非小细胞肺癌生存率的时间趋势。

Temporal trends in non-small cell lung cancer survival in Sweden.

作者信息

Brooks D R, Klint A, Dickman P W, Ståhle E, Lambe M

机构信息

Department of Epidemiology, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA.

出版信息

Br J Cancer. 2007 Feb 12;96(3):519-22. doi: 10.1038/sj.bjc.6603591. Epub 2007 Jan 23.

DOI:10.1038/sj.bjc.6603591
PMID:17245337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2360026/
Abstract

We modeled temporal trends in the 1- and 5-year survival of 32 499 patients with adenocarcinoma and squamous cell carcinoma of the lung in the Swedish Cancer Register between 1961 and 2000. The 1-year relative survival for adenocarcinoma improved from 37% for patients diagnosed 1961-1965 to 45% for those diagnosed 1996-2000 and from 39 to 45% for squamous cell carcinoma. The adjusted excess mortality ratios for the period 1996-2000 compared with 1961-1965 were 0.80 for adenocarcinoma and 0.81 for squamous cell carcinoma. Thus, a previous report in a Dutch study of a relatively worsening prognosis for adenocarcinoma over time could not be confirmed.

摘要

我们对瑞典癌症登记处1961年至2000年间32499例肺腺癌和肺鳞状细胞癌患者的1年和5年生存率的时间趋势进行了建模。腺癌患者的1年相对生存率从1961 - 1965年诊断的患者的37%提高到1996 - 2000年诊断的患者的45%，鳞状细胞癌患者的这一比例从39%提高到45%。与1961 - 1965年相比，1996 - 2000年期间腺癌的调整后超额死亡率比值为0.80，鳞状细胞癌为0.81。因此，荷兰一项研究中关于腺癌预后随时间相对恶化的先前报告无法得到证实。