Martínez-Lavín M
Rheumatology Department, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano no. 1, 14080 México D.F. Mexico.
Clin Exp Rheumatol. 2001 Jan-Feb;19(1):1-3.
Fibromyalgia and reflex sympathetic dystrophy share defining characteristics, namely chronic pain and allodynia, as well as other important clinical features such as onset after trauma, female predominance, paresthesias, vasomotor instability, response to sympathetic blockade and anxiety/depression. Recent research using heart rate variability analysis demonstrated that patients with fibromyalgia have changes consistent with relentless circadian sympathetic hyperactivity. I propose that fibromyalgia is a sympathetically maintained pain syndrome in which ongoing sympathetic hyperactivity sensitises the primary nociceptors and induces widespread pain and allodynia.
纤维肌痛症和反射性交感神经营养不良具有一些共同的特征，即慢性疼痛和痛觉过敏，以及其他重要的临床特征，如创伤后发病、女性居多、感觉异常、血管运动不稳定、对交感神经阻滞的反应以及焦虑/抑郁。最近使用心率变异性分析的研究表明，纤维肌痛症患者存在与持续的昼夜交感神经过度活跃相一致的变化。我认为纤维肌痛症是一种由交感神经维持的疼痛综合征，其中持续的交感神经过度活跃使初级伤害感受器敏感化，并引发广泛的疼痛和痛觉过敏。
