Krivorutchenko Iu L
Crimean Medical University, Department of Microbiology, 5/7 Lenin Blvd., Simferopol, Crimea, 95006, Ukraine.
Mikrobiol Z. 2000 Nov-Dec;62(6):33-9.
The effect of some saponins (taurosides) and muramyl peptides (MDP and cholesteryl-MDP) on HIV-1 reproduction in Jurkat-tat T cells was studied by the coefficient of the virus expression CE. CE was calculated as ratio of concentration of HIV p24 to the amount of viable cells. Various substances caused diverse effects on HIV-1 propagation (taurosid I and cholesteryl-MDP possessed potent antiviral and HIV-stimulating properties respectively). The effectiveness of the CE usage for detection of HIV-modulating characteristics of various substances was discussed.
通过病毒表达系数CE研究了某些皂苷（牛磺苷）和胞壁酰肽（MDP和胆固醇基-MDP）对Jurkat-tat T细胞中HIV-1复制的影响。CE计算为HIV p24浓度与活细胞数量的比值。各种物质对HIV-1的传播产生了不同的影响（牛磺苷I和胆固醇基-MDP分别具有强大的抗病毒和刺激HIV的特性）。讨论了使用CE检测各种物质的HIV调节特性的有效性。
