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2-氰基丙烯酸辛酯医用粘合剂治疗角膜穿孔

2-Octyl cyanoacrylate medical adhesive in treatment of a corneal perforation.

作者信息

Taravella M J, Chang C D

机构信息

Department of Ophthalmology, University of Colorado, Denver, USA.

出版信息

Cornea. 2001 Mar;20(2):220-1. doi: 10.1097/00003226-200103000-00024.

DOI:10.1097/00003226-200103000-00024
PMID:11248835
Abstract

PURPOSE

To describe a case of successful treatment of a corneal perforation with 2-octyl cyanoacrylate.

METHODS

2-Octyl cyanoacrylate was applied at the slit lamp with topical proparacaine anesthesia to a cornea with an inferior perforation with iris plugging the defect.

RESULTS

After application of 2-octyl cyanoacrylate, the anterior chamber was noted to deepen, and visual acuity improved to 20/200. The glue remained intact for more than 6 weeks and eventually fell out. The underlying cornea healed without scarring, vascularization, or thinning.

CONCLUSION

We have described a case in which 2-octyl cyanoacrylate was used to treat a corneal perforation with excellent results. Further study of this adhesive will be useful in comparing the effectiveness and safety of 2-octyl cyanoacrylate with that of previously studied adhesives.

摘要

目的

描述一例使用2-氰基丙烯酸辛酯成功治疗角膜穿孔的病例。

方法

在裂隙灯下,于表面丙美卡因麻醉下,将2-氰基丙烯酸辛酯应用于一处下方有穿孔且虹膜堵塞缺损处的角膜。

结果

应用2-氰基丙烯酸辛酯后,前房变深,视力提高至20/200。胶水保持完整超过6周,最终脱落。下方角膜愈合,无瘢痕形成、血管化或变薄。

结论

我们描述了一例使用2-氰基丙烯酸辛酯治疗角膜穿孔且效果极佳的病例。对这种黏合剂进行进一步研究,将有助于比较2-氰基丙烯酸辛酯与先前研究的黏合剂在有效性和安全性方面的差异。

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