Moschos M, Droutsas D, Boussalis P, Tsioulias G
Department of Ophthalmology, University of Athens, Greece.
Doc Ophthalmol. 1996;93(3):237-45. doi: 10.1007/BF02569064.
In this paper 385 cases treated with cyanoacrylate tissue adhesive during the years 1980-1995 are studied. The indications, outcomes and complications of cyanoacrylate adhesive are investigated and the results are analysed. It is encouraging that except for three cases of ocular hypotony and two cases of microbial infection no other complications occurred. Even in desperate cases with corneal perforation greater than 3 mm and ocular infection, enucleation was avoided. The early use of a bandage contact lens, inserted just after the glue application and the coverage with topical antibiotics switched every 15 days until the removal of the glue, may explain the small incidence of infection. Our experience from the use of cyanoacrylate tissue adhesive in cases with corneal perforation greater than 3 mm is very encouraging. In these cases a running 10.0 nylon suture was used to create a reticulum over the space of the corneal perforation upon which the glue was applied. The use of cyanoacrylate tissue adhesive offers to the clinician a safe technique for healing corneal wounds that avoids tectonic penetrating keratoplasty with its associated complications.
本文研究了1980年至1995年间用氰基丙烯酸酯组织粘合剂治疗的385例病例。对氰基丙烯酸酯粘合剂的适应症、治疗结果和并发症进行了调查并分析了结果。令人鼓舞的是，除3例眼压过低和2例微生物感染外，未发生其他并发症。即使在角膜穿孔大于3mm且伴有眼部感染的绝望病例中，也避免了眼球摘除。早期使用绷带式隐形眼镜，在涂抹胶水后立即插入，并每15天更换一次局部抗生素覆盖物，直至胶水去除，这可能是感染发生率低的原因。我们在角膜穿孔大于3mm的病例中使用氰基丙烯酸酯组织粘合剂的经验非常令人鼓舞。在这些病例中，使用连续的10.0尼龙缝线在角膜穿孔处形成一个网状结构，然后在其上涂抹胶水。氰基丙烯酸酯组织粘合剂的使用为临床医生提供了一种安全的角膜伤口愈合技术，避免了穿透性角膜移植术及其相关并发症。
