Skare O C, Wisnes A R
Department of Physiology, University of Bergen, Norway.
Scand J Med Sci Sports. 2001 Apr;11(2):96-102. doi: 10.1034/j.1600-0838.2001.011002096.x.
The object of this study was to evaluate the effect of creatine (Cr) supplementation in well trained male sprinters. The study was performed as a single blind test on 18 sprinters at a local competition level. During the last two years a substantial part of their training had consisted of a series of maximal sprints with short rest periods to improve their fatigue resistance. The participants consumed either 20 g Cr+20 g glucose per day (Cr group, n=9) or 40 g glucose per day (placebo group, n=9), divided into 4 equal dosages. The effect of Cr on sprint performance was evaluated in two tests, 1 x 100 m sprint and an intermittent 6x60 m sprint. Cr supplementation increased the 100 m sprint velocity (11.68+/-0.27 s vs 11.59+/-0.31 s) and reduced the total time of 6 intermittent 60 m sprints (45.63+/-1.11 s vs 45.12+/-1.1 s), whereas no changes were observed in the placebo group. The sprint velocity was significantly increased in 5 out of 6 intermittent 60 m sprints. Venous blood was drawn 5 min after finishing the final intermittent 60 m run. Plasma lactate, Cr and serum creatinine (Crn) were all increased in the Cr group compared to presupplementation values; no changes were observed in the placebo group. The improved sprint performance suggests an increased availability of energy substrate for performing work, possibly as a result of increased skeletal muscle creatine phosphate (PCr).
本研究的目的是评估补充肌酸（Cr）对训练有素的男性短跑运动员的影响。该研究对18名当地比赛水平的短跑运动员进行了单盲测试。在过去两年中，他们的大部分训练包括一系列短休息时间的最大冲刺跑，以提高他们的抗疲劳能力。参与者每天服用20克Cr + 20克葡萄糖（Cr组，n = 9）或每天40克葡萄糖（安慰剂组，n = 9），分为4等份剂量。通过1次100米冲刺跑和6次60米间歇冲刺跑两项测试评估Cr对短跑成绩的影响。补充Cr提高了100米冲刺跑速度（11.68±0.27秒对11.59±0.31秒），并缩短了6次60米间歇冲刺跑的总时间（45.63±1.11秒对45.12±1.1秒），而安慰剂组未观察到变化。在6次60米间歇冲刺跑中的5次中，冲刺跑速度显著提高。在完成最后一次60米间歇跑后5分钟采集静脉血。与补充前的值相比，Cr组的血浆乳酸、Cr和血清肌酐（Crn）均升高；安慰剂组未观察到变化。短跑成绩的提高表明用于做功的能量底物可用性增加，这可能是骨骼肌磷酸肌酸（PCr）增加的结果。
