Stupans I, Jones B, McKinnon R A
Centre for Pharmaceutical Research, School of Pharmacy and Medical Sciences, University of South Australia, North Terrace, SA, 5000, Adelaide, Australia.
Comp Biochem Physiol C Toxicol Pharmacol. 2001 Mar;128(3):367-76. doi: 10.1016/s1532-0456(00)00211-8.
The Australian marsupials are significant and unique Australian fauna. Xenobiotic metabolism is the process of enzymatic modification of xenobiotics, which include the chemicals, such as agricultural chemicals and natural dietary toxins, that these animals may be exposed to. Very little is known about the enzymes involved in xenobiotic metabolism in this unique group of animals. Folivore marsupials such as the koala (Phascolarctos cinereus and the brushtail possum (Trichosurus vulpecula) represent unique adaptation which has only been relatively superficially examined to date. We provide an overview of our current knowledge of marsupial xenobiotic metabolism.
澳大利亚有袋类动物是澳大利亚重要且独特的动物群。异生物质代谢是对外源生物进行酶促修饰的过程，这些外源生物包括这些动物可能接触到的化学物质，如农用化学品和天然饮食毒素。对于这一独特动物群体中参与异生物质代谢的酶，我们知之甚少。食叶有袋类动物，如树袋熊（Phascolarctos cinereus）和刷尾负鼠（Trichosurus vulpecula），代表了一种独特的适应性，迄今为止仅得到相对肤浅的研究。我们概述了目前关于有袋类动物异生物质代谢的知识。
