乳腺癌患者的羟脯氨酸排泄及对治疗的反应。
Hydroxyproline excretion in patients with breast cancer and response to treatment.
作者信息
Powles T J, Leese C L, Bondy P K
出版信息
Br Med J. 1975 Apr 26;2(5964):164-6. doi: 10.1136/bmj.2.5964.164.
Abstract
The urinary excretion of hydroxyproline, measured as the hydroxyproline: creatinine ratio, was useful in monitoring the progression of metastatic cancer of the breast. After new treatment was started changes in the hydroxyproline excretion occurred earlier than other clinically observable responses. The test could therefore be used for predicting the response to treatment and early detection of the sensitivity of the tumour to hormone therapy.
摘要
以羟脯氨酸与肌酐的比值来衡量的羟脯氨酸尿排泄量，在监测乳腺癌转移癌的进展方面很有用。开始新的治疗后，羟脯氨酸排泄量的变化比其他临床可观察到的反应出现得更早。因此，该检测可用于预测治疗反应以及早期检测肿瘤对激素治疗的敏感性。
相似文献
1
Hydroxyproline excretion in patients with breast cancer and response to treatment.乳腺癌患者的羟脯氨酸排泄及对治疗的反应。
Br Med J. 1975 Apr 26;2(5964):164-6. doi: 10.1136/bmj.2.5964.164.
2
Early morning hydroxyproline excretion in patients with breast cancer.
Cancer. 1976 Dec;38(6):2564-6. doi: 10.1002/1097-0142(197612)38:6<2564::aid-cncr2820380648>3.0.co;2-w.
3
Relevance of hydroxyproline excretion to bone metastasis in breast cancer.羟脯氨酸排泄与乳腺癌骨转移的相关性
Br J Cancer. 1976 Sep;34(3):279-85. doi: 10.1038/bjc.1976.163.
4
[Urinary hydroxyproline excretion before and after hypophysectomy in patients with bone metastases from breast cancer].[乳腺癌骨转移患者垂体切除术前、后的尿羟脯氨酸排泄情况]
Ugeskr Laeger. 1968 Oct 17;130(42):1766-71.
5
Urinary hydroxyproline excretion in patients with breast cancer.乳腺癌患者尿羟脯氨酸排泄情况
Br J Surg. 1971 Nov;58(11):862.
6
[Hydroxyproline in the diagnosis of bone metastases in breast cancer].[羟脯氨酸在乳腺癌骨转移诊断中的应用]
Schweiz Med Wochenschr. 1977 Jul 16;107(28):984-6.
7
Urinary hydroxyproline excretion in carcinoma of the breast.乳腺癌患者尿中羟脯氨酸的排泄情况
Br J Exp Pathol. 1972 Jun;53(3):237-41.
8
Total urinary hydroxyproline excretion before and after hypophysectomy in patients with bone metastases from breast carcinoma.乳腺癌骨转移患者垂体切除术前、后的尿羟脯氨酸总排泄量。
Acta Endocrinol (Copenh). 1968 Nov;59(3):353-61. doi: 10.1530/acta.0.0590353.
9
Urinary hydroxyproline excretion in patients with cancer.癌症患者尿羟脯氨酸排泄情况
Cancer. 1969 Aug;24(2):382-7. doi: 10.1002/1097-0142(196908)24:2<382::aid-cncr2820240221>3.0.co;2-s.
10
[Hydroxyproline excretion as an index for the evaluation of metabolic bone changes].[以羟脯氨酸排泄作为评估代谢性骨变化的指标]
Beitr Orthop Traumatol. 1966 Oct;13(10):606-8.
引用本文的文献
1
Free serum hydroxyproline and total urinary hydroxyproline for the detection of skeletal metastasis.游离血清羟脯氨酸和尿总羟脯氨酸用于检测骨转移。
Br J Cancer. 1982 Mar;45(3):477-81. doi: 10.1038/bjc.1982.78.
2
Lack of hormonal changes in postmenopausal women of equal weight with and without osteoporosis, including relation to time of menopause.体重相同的绝经后女性中，患有和未患骨质疏松症者的激素变化情况，包括与绝经时间的关系。
Clin Rheumatol. 1984 Sep;3(3):337-43. doi: 10.1007/BF02032340.
3
Relevance of hydroxyproline excretion to bone metastasis in breast cancer.羟脯氨酸排泄与乳腺癌骨转移的相关性
Br J Cancer. 1976 Sep;34(3):279-85. doi: 10.1038/bjc.1976.163.
4
Urinary hydroxyproline in the management of breast cancer.尿羟脯氨酸在乳腺癌治疗中的应用
World J Surg. 1977 May;1(3):299-302. doi: 10.1007/BF01556842.
5
Calcium metabolism in breast cancer.乳腺癌中的钙代谢
Proc R Soc Med. 1977 Mar;70(3):195-9. doi: 10.1177/003591577707000318.
6
Three-centre study on urinary hydroxyproline excretion in cancer of the breast.关于乳腺癌患者尿羟脯氨酸排泄的三中心研究。
Br J Cancer. 1978 Jun;37(6):1002-5. doi: 10.1038/bjc.1978.145.
7
Evaluation of biochemical markers in breast cancer.乳腺癌中生化标志物的评估。
Proc R Soc Med. 1977 Dec;70(12):843-5. doi: 10.1177/003591577707001205.
8
Total urinary and free serum hydroxyproline in metastatic bone disease.转移性骨病中尿总羟脯氨酸和游离血清羟脯氨酸
Br J Cancer. 1979 Mar;39(3):280-3. doi: 10.1038/bjc.1979.52.
9
Agents affecting osteolysis in patients with breast cancer.影响乳腺癌患者骨溶解的因素
Cancer Chemother Pharmacol. 1979;3(1):41-4. doi: 10.1007/BF00254418.
本文引用的文献
1
ISOTOPIC STUDIES ON COLLAGEN DEGRADATION AND THE URINE EXCRETION OF HYDROXYPROLINE.关于胶原蛋白降解及羟脯氨酸尿排泄的同位素研究。
J Clin Invest. 1964 Mar;43(3):453-60. doi: 10.1172/JCI104930.
2
3
A specific method for the analysis of hydroxyproline in tissues and urine.一种用于分析组织和尿液中羟脯氨酸的特定方法。
Anal Biochem. 1960 Nov;1:228-39. doi: 10.1016/0003-2697(60)90050-6.
4
Influence of estradiol and estriol on urinary excretion of hydroxyproline in man.雌二醇和雌三醇对人体尿中羟脯氨酸排泄的影响。
J Lab Clin Med. 1968 Jan;71(1):65-74.
5
The inhibition by aspirin and indomethacin of osteolytic tumor deposits and hypercalcaemia in rats with Walker tumour, and its possible application to human breast cancer.阿司匹林和吲哚美辛对Walker瘤大鼠溶骨性肿瘤沉积物及高钙血症的抑制作用及其在人类乳腺癌中的可能应用。
Br J Cancer. 1973 Oct;28(4):316-21. doi: 10.1038/bjc.1973.154.
6
Urinary hydroxyproline excretion in early and advanced breast cancer-a sequential study.早期及进展期乳腺癌患者尿羟脯氨酸排泄情况的序贯研究
Br J Surg. 1973 Oct;60(10):800-3. doi: 10.1002/bjs.1800601012.
7
'Early' breast cancer, bone scanning, and the urinary excretion of hydroxyproline.“早期”乳腺癌、骨扫描与羟脯氨酸的尿排泄
Br J Surg. 1973 Apr;60(4):306.
Zotero 插件