Berman S J, Johnson E W
Hawaii Med J. 2001 Feb;60(2):31-3.
A chart review was conducted of patients in a program featuring self directed, home infusion of antibiotics for serious infections utilizing an out-patient medical office for teaching, mixing of drugs, and monitoring of patients. 302 courses of out-patient parenteral antibiotic therapy (OPAT) were administered to 221 patients. Therapy was successful in 94% of the episodes. Objective adverse events were noted in 25% of patients. To maximize the chance for a successful outcome, treatment plans should be individualized and structured to include systematic monitoring for adverse effects.
对一个项目中的患者进行了病历审查，该项目的特点是患者自我指导在家输注抗生素以治疗严重感染，利用门诊医疗办公室进行教学、药物混合和患者监测。共对221名患者进行了302个疗程的门诊胃肠外抗生素治疗（OPAT）。94%的疗程治疗成功。25%的患者出现了客观不良事件。为了最大限度地提高成功治疗的几率，治疗计划应个性化并结构化，包括对不良反应的系统监测。
