Takahashi K, Takahashi E, Ducusin R J, Tanabe S, Uzuka Y, Sarashina T
Department of Veterinary Internal Medicine, Obihiro University of Agriculture and Veterinary Medicine, Japan.
J Vet Med Sci. 2001 Feb;63(2):175-8. doi: 10.1292/jvms.63.175.
Maximum serum thyroxine (T4) and triiodothyronine (T3) levels of healthy calves were seen at 1 day after birth, and thereafter rapidly decreased until 5 days after birth. They stabilized until 2 weeks after birth, then gradually decreased until 4 weeks after birth. Serum T4 levels of calves with endemic goiter tended to be lower than those of healthy ones, but showed similar levels to those of adult cows. T3 levels of calves with goiter were similar to those of healthy ones, but showed higher variation. T4/T3 ratio of calves with goiter were significantly lower than those of healthy ones and adult cows. While individual levels of serum T4 and T3 at just after birth could not be considered as a diagnostic index, the T4/T3 ratio could be adopted as a diagnostic index of endemic goiter.
健康犊牛的血清甲状腺素(T4)和三碘甲状腺原氨酸(T3)水平在出生后1天达到最高,此后迅速下降,直至出生后5天。它们在出生后2周内保持稳定,然后逐渐下降,直至出生后4周。地方性甲状腺肿犊牛的血清T4水平往往低于健康犊牛,但与成年母牛的水平相似。甲状腺肿犊牛的T3水平与健康犊牛相似,但变化较大。甲状腺肿犊牛的T4/T3比值显著低于健康犊牛和成年母牛。虽然出生后即刻的血清T4和T3个体水平不能作为诊断指标,但T4/T3比值可作为地方性甲状腺肿的诊断指标。