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新生犊牛不同品种中的甲状腺素、三碘甲状腺原氨酸和碘化物。

Thyroxine, triiodothyronine and iodide in different breeds of newborn calves.

作者信息

Davicco M J, Vigouroux E, Dardillat C, Barlet J P

出版信息

Reprod Nutr Dev (1980). 1982;22(2):355-62. doi: 10.1051/rnd:19820306.

DOI:10.1051/rnd:19820306
PMID:7156485
Abstract

Plasma thyroxine (T4), triiodothyronine (T3) and iodide levels were measured from birth until 30 days of age in 17 Holstein x Friesian (HF), 7 Salers and 7 Charolais calves born at term. The response of plasma T4 and T3 levels to bovine thyrotropin (TSH) injection was also compared in two groups of 9 HF calves 3hrs and 21 days, respectively, after birth. In the HF calves, plasma T4 and T3 levels increased from birth to 6 hrs (when the rectal temperature of these calves decreased slightly), then diminished until day 7 and remained stable until 30 days of age. In Salers calves, changes in the plasma T4 and T3 levels were not different from those observed in HF animals. However, in Charolais calves, there was no significant increase in plasma T4 and T3 levels after birth. Twelve and 24 hrs after birth, the plasma iodothyronine levels measured in these animals were lower than in HF calves. In Salers and Charolais calves a positive linear relationship was demonstrated between plasma T4 (or T3) levels at birth and the birth weight. In the three groups of calves, plasma iodide levels decreased from birth until 10 days of age, then remained stable until the end of the first neonatal month. Intravenous injection of the same dose of bovine TSH (5 mU/kg of body weight) induced a rise in the plasma T4 and T3 levels which was significantly more intense in 21-day old calves than in 3-hr old calves.

摘要

对17头足月出生的荷斯坦×弗里生(HF)、7头萨勒斯和7头夏洛来犊牛,从出生到30日龄期间测定其血浆甲状腺素(T4)、三碘甲状腺原氨酸(T3)和碘水平。还分别对两组各9头HF犊牛在出生后3小时和21天时注射牛促甲状腺激素(TSH)后的血浆T4和T3水平反应进行了比较。在HF犊牛中,血浆T4和T3水平从出生到6小时(此时这些犊牛的直肠温度略有下降)升高,然后下降直至第7天,并一直保持稳定直至30日龄。在萨勒斯犊牛中,血浆T4和T3水平的变化与HF动物中观察到的情况无差异。然而,在夏洛来犊牛中,出生后血浆T4和T3水平没有显著升高。在这些动物出生后12小时和24小时测量的血浆碘甲状腺原氨酸水平低于HF犊牛。在萨勒斯和夏洛来犊牛中,出生时血浆T4(或T3)水平与出生体重之间呈正线性关系。在三组犊牛中,血浆碘水平从出生到10日龄下降,然后保持稳定直至第一个新生儿月结束。静脉注射相同剂量的牛TSH(5 mU/kg体重)导致血浆T4和T3水平升高,21日龄犊牛的升高幅度明显大于3小时龄犊牛。

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