Murakami Y, Uchida K, Yamaguchi R, Tateyama S
Department of Veterinary Pathology, Faculty of Agriculture, Miyazaki University, Gakuen Kibana Dai, Japan.
J Vet Med Sci. 2001 Feb;63(2):191-3. doi: 10.1292/jvms.63.191.
A 15-year-old female mongrel dog showed abdominal swelling, marked hemorrhagic ascites and vulvar discharge, and ovariohysterectomy was performed. Grossly, the uterus was enlarged bilaterally without apparent mass formation. Histologically, the uterine muscular wall was composed of proliferated sinusoidal vessels. In some areas, irregular and small vessels proliferated markedly, while in others, pleomorphic and atypical tumor cells forming irregular vascular structures were predominant. From these findings, the case was diagnosed as diffuse bilateral hemangiosarcoma of the uterus that invaded to the ovary and broad ligament. The relationship between the tumor and angiomatosis was discussed.
一只15岁的雌性杂种犬出现腹部肿胀、明显的出血性腹水和阴门排出物，遂进行了卵巢子宫切除术。大体检查时，子宫双侧增大，无明显肿块形成。组织学检查显示，子宫肌壁由增生的窦状血管组成。在一些区域，不规则的小血管明显增生，而在其他区域，形成不规则血管结构的多形性和非典型肿瘤细胞占主导。根据这些发现，该病例被诊断为子宫弥漫性双侧血管肉瘤，已侵犯卵巢和阔韧带。并对该肿瘤与血管瘤病之间的关系进行了讨论。
