Laboratory of Veterinary Clinical Oncology, Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Laboratory of Veterinary Pathology, Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.
Vet Med Sci. 2024 Jan;10(1):e1311. doi: 10.1002/vms3.1311. Epub 2023 Nov 21.
A 7-year-old intact Netherlands Dwarf rabbit with bloody discharge from the vulva underwent ovariohysterectomy. Grossly, both sides of the uterus were enlarged. Histologically, the tumour had formed protruded from the myometrial wall toward the serosa and was composed of irregular small capillaries with irregularly shaped structures and bundled proliferation of spindle-shaped cells. No tumour cells infiltrated the endometrium. The tumour cells were positive for CD31, and histological and immunohistochemical staining confirmed the diagnosis of haemangiosarcoma. Vascular tumours in the uterus of animals are uncommon, and only one case has been reported in the uterus of rabbits.
一只 7 岁的未绝育荷兰侏儒兔从阴道排出血性分泌物，接受了卵巢子宫切除术。大体检查发现，两侧子宫均肿大。组织学上，肿瘤从子宫肌壁向浆膜突出，由不规则的小毛细血管组成，形状不规则的结构和梭形细胞束状增生。肿瘤细胞未浸润子宫内膜。肿瘤细胞 CD31 阳性，组织学和免疫组织化学染色证实为血管肉瘤的诊断。动物子宫内的血管肿瘤并不常见，仅在一例兔子的子宫中报告过。
