• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

蜂花粉在一名不知情的致敏个体中引发过敏反应。

Bee pollen-induced anaphylactic reaction in an unknowingly sensitized subject.

作者信息

Greenberger P A, Flais M J

机构信息

Division of Allergy-Immunology and the Ernest S. Bazley Asthma and Allergic Diseases Center of Northwestern Memorial Hospital and Northwestern University Medical School, Chicago, Illinois 60611-3008, USA.

出版信息

Ann Allergy Asthma Immunol. 2001 Feb;86(2):239-42. doi: 10.1016/S1081-1206(10)62698-1.

DOI:10.1016/S1081-1206(10)62698-1
PMID:11258697
Abstract

BACKGROUND

The food supplement bee pollen has been previously found to cause anaphylactic reactions. It has been proposed as useful for "everything from bronchitis to hemorrhoids."

OBJECTIVE

This study describes an atopic patient who experienced a non-life-threatening anaphylactic reaction upon her initial ingestion of bee pollen. Microscopic examination of the pollen sample and ELISA inhibition assays were performed.

RESULTS

The patient had a 7 mm/28 mm wheal/erythema reaction to bee pollen at 1 mg/mL concentration. Bee pollen caused 52% inhibition of IgE binding to short ragweed and 55% to ryegrass. Microscopic analysis revealed ragweed, Alternaria, Cladosporium, honeysuckle (Lonicera sp), privet shrub (Ligustrum sp), and vetch (Vicia sativa).

CONCLUSIONS

An unknowingly sensitized atopic patient experienced an anaphylactic reaction after ingestion of a small quantity of bee pollen that contained pollens and fungi. Previously administered allergen immunotherapy that had reduced rhinitis symptoms did not prevent this allergic reaction.

摘要

背景

先前已发现食品补充剂蜂花粉会引起过敏反应。有人提出它对“从支气管炎到痔疮的各种疾病”都有用。

目的

本研究描述了一名特应性患者,她在首次摄入蜂花粉后经历了一次非危及生命的过敏反应。对花粉样本进行了显微镜检查和酶联免疫吸附测定抑制试验。

结果

患者对浓度为1mg/mL的蜂花粉出现了7mm/28mm的风团/红斑反应。蜂花粉对短豚草的IgE结合有52%的抑制作用,对黑麦草有55%的抑制作用。显微镜分析显示有豚草、链格孢属、枝孢属、金银花(忍冬属)、女贞(女贞属)和野豌豆(野豌豆)。

结论

一名不知情已致敏的特应性患者在摄入含有花粉和真菌的少量蜂花粉后发生了过敏反应。先前进行的已减轻鼻炎症状的变应原免疫疗法未能预防此次过敏反应。

相似文献

1
Bee pollen-induced anaphylactic reaction in an unknowingly sensitized subject.蜂花粉在一名不知情的致敏个体中引发过敏反应。
Ann Allergy Asthma Immunol. 2001 Feb;86(2):239-42. doi: 10.1016/S1081-1206(10)62698-1.
2
Anaphylactic reaction after ingestion of local bee pollen.食用本地蜂花粉后发生过敏反应。
Ann Allergy. 1981 Sep;47(3):154-6.
3
Allergy caused by ingestion of zucchini (Cucurbita pepo): characterization of allergens and cross-reactivity to pollen and other foods.食用西葫芦(南瓜属)引起的过敏:过敏原的特征以及与花粉和其他食物的交叉反应
J Allergy Clin Immunol. 2000 Aug;106(2):379-85. doi: 10.1067/mai.2000.107602.
4
Anaphylaxis caused by artisanal honey in a child: a case report.儿童因食用手工蜂蜜而引发的过敏反应:病例报告。
J Med Case Rep. 2021 May 14;15(1):235. doi: 10.1186/s13256-021-02823-4.
5
Anaphylaxis to honey in pollinosis to mugwort: a case report.蒿草花粉症患者对蜂蜜过敏:一例报告
Eur Ann Allergy Clin Immunol. 2006 Dec;38(10):364-5.
6
Bee pollen: a dangerous food for allergic children. Identification of responsible allergens.蜂花粉:过敏儿童的危险食物。确定相关过敏原。
Allergol Immunopathol (Madr). 2010 Sep-Oct;38(5):263-5. doi: 10.1016/j.aller.2009.12.003. Epub 2010 May 5.
7
Profilin sensitization detected in the office by skin prick test: a study of prevalence and clinical relevance of profilin as a plant food allergen.通过皮肤点刺试验在门诊检测到的肌动蛋白结合蛋白致敏:关于肌动蛋白结合蛋白作为植物性食物过敏原的患病率及临床相关性的研究
Clin Exp Allergy. 2008 Jun;38(6):1033-7. doi: 10.1111/j.1365-2222.2008.02980.x. Epub 2008 Apr 13.
8
Artemisia and Ambrosia hypersensitivity: co-sensitization or co-recognition?艾蒿和豚草过敏:共同致敏还是共同识别?
Clin Exp Allergy. 2006 May;36(5):658-65. doi: 10.1111/j.1365-2222.2006.02477.x.
9
Array-based profiling of ragweed and mugwort pollen allergens.基于芯片技术的豚草和艾蒿花粉过敏原分析
Allergy. 2008 Nov;63(11):1543-9. doi: 10.1111/j.1398-9995.2008.01780.x.
10
Soybean allergy in patients allergic to birch pollen: clinical investigation and molecular characterization of allergens.对桦树花粉过敏患者的大豆过敏:过敏原的临床研究与分子特征分析
J Allergy Clin Immunol. 2004 Jan;113(1):148-54. doi: 10.1016/j.jaci.2003.09.030.

引用本文的文献

1
Recent Advances in the Allergic Cross-Reactivity between Fungi and Foods.真菌与食物之间过敏交叉反应的最新进展。
J Immunol Res. 2022 Oct 7;2022:7583400. doi: 10.1155/2022/7583400. eCollection 2022.
2
A paediatric case of exercise-augmented anaphylaxis following bee pollen ingestion in Western Australia.澳大利亚西部一名儿童在摄入蜂花粉后出现运动加剧型过敏反应的病例。
Asia Pac Allergy. 2022 Jul 12;12(3):e23. doi: 10.5415/apallergy.2022.12.e23. eCollection 2022 Jul.
3
Bee Pollen: Current Status and Therapeutic Potential.蜂花粉:现状与治疗潜力。
Nutrients. 2021 May 31;13(6):1876. doi: 10.3390/nu13061876.
4
Toxicological Risk Assessment of the Accidental Ingestion of a Honeybee ( L.) Present in Food.食品中意外摄入蜜蜂(L.)的毒理学风险评估。
Front Vet Sci. 2020 Sep 30;7:583286. doi: 10.3389/fvets.2020.583286. eCollection 2020.
5
Bee Pollen-Induced Anaphylaxis: A Case Report and Literature Review.蜂花粉诱发的过敏反应:一例报告及文献综述
Allergy Asthma Immunol Res. 2015 Sep;7(5):513-7. doi: 10.4168/aair.2015.7.5.513. Epub 2014 Oct 15.
6
Pathogenesis, newly recognized etiologies, and management of idiopathic anaphylaxis.特发性过敏反应的发病机制、新发现的病因及管理
Discov Med. 2015 Feb;19(103):137-44.
7
A cross-sectional survey on dietary supplements consumption among Italian teen-agers.一项关于意大利青少年膳食补充剂消费情况的横断面调查。
PLoS One. 2014 Jul 2;9(7):e100508. doi: 10.1371/journal.pone.0100508. eCollection 2014.
8
Anaphylaxis from bee pollen supplement.蜂花粉补充剂引起的过敏反应。
CMAJ. 2012 Jul 10;184(10):1167-9. doi: 10.1503/cmaj.112181. Epub 2012 May 22.
9
Surveillance of suspected adverse reactions to natural health products: the case of propolis.天然健康产品疑似不良反应监测:蜂胶案例
Drug Saf. 2008;31(5):419-23. doi: 10.2165/00002018-200831050-00007.