使用新型抗抑郁药患者的用药模式。
Prescribing patterns in patients using new antidepressants.
作者信息
Meijer W E, Heerdink E R, Pepplinkhuizen L P, van Eijk J T, Leufkens H G
机构信息
Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, The Netherlands.
出版信息
Br J Clin Pharmacol. 2001 Feb;51(2):181-3. doi: 10.1111/j.1365-2125.2001.01329.x.
AIMS
To study possible selective prescribing ('channelling') we compared characteristics of patients using the SSRI sertraline with patients using longer available SSRIs.
METHODS
An observational cohort study in 1251 patients being prescribed an SSRI.
RESULTS
In contrast to other studies, we found no evidence for channeling of sertraline. Sertraline was mainly prescribed for the labelled indication (depressive disorder), while older SSRIs were more often prescribed also for other indications. Time on the market was inversely associated to the proportion of patients treated for depressive disorder.
CONCLUSIONS
We found no evidence for channeling of sertraline compared with prescribing patterns of older SSRIs.
目的
为研究可能存在的选择性处方用药（“引导用药”）情况，我们比较了使用选择性5-羟色胺再摄取抑制剂（SSRI）舍曲林的患者与使用上市时间更长的SSRI类药物的患者的特征。
方法
对1251名正在使用SSRI类药物的患者进行观察性队列研究。
结果
与其他研究不同，我们未发现舍曲林存在引导用药的证据。舍曲林主要用于其标注的适应证（抑郁症），而较老的SSRI类药物更多地还用于其他适应证。上市时间与接受抑郁症治疗的患者比例呈负相关。
结论
与较老的SSRI类药物的处方模式相比，我们未发现舍曲林存在引导用药的证据。
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