Mendelson J H, Mello N K
Clin Pharmacol Ther. 1975 May;17(5):529-33. doi: 10.1002/cpt1975175529.
The effects of heroin use and subsequent prolonged abstinence on plasma testosterone levels were examined in 31 male heroin addicts. Heroin (alone and in combination with methadone) significantly suppressed plasma testosterone levels. However, drug-induced testosterone suppression does not appear to be permanent in adult addicts. Recovery of testosterone levels to normal occurred after about one month of heroin abstinence.
对31名男性海洛因成瘾者研究了使用海洛因及随后长期戒毒对血浆睾酮水平的影响。海洛因(单独使用及与美沙酮联合使用)显著抑制血浆睾酮水平。然而,药物引起的睾酮抑制在成年成瘾者中似乎并非永久性的。在戒除海洛因约一个月后,睾酮水平恢复正常。