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年龄对大鼠脂肪组织中脱氧核糖核酸合成的影响。

The effect of age on deoxyribonucleic acid synthesis in rat adipose tissue.

作者信息

Lewis B M, Hayes T M

出版信息

Clin Sci Mol Med. 1975 Apr;48(4):323-5. doi: 10.1042/cs0480323.

DOI:10.1042/cs0480323
PMID:1126123
Abstract
  1. Rats of four different age groups were injected intraperitoneally with labelled thymidine and killed 1, 7 or 12 days later. 2. The epididymal fat-pads were separated into fat-cells and stromal elements by collagenase digestion. 3. The incorporation of labelled thymidine into the deoxyribonucleic acid (DNA) of both fractions was greatest in the 6-week-old animals. Uptake was significantly decreased in 12- and 15-week-old animals and was lowest in 22-week-old rats.
摘要
  1. 给四个不同年龄组的大鼠腹腔注射标记的胸腺嘧啶核苷,并在1、7或12天后处死。2. 通过胶原酶消化将附睾脂肪垫分离为脂肪细胞和基质成分。3. 两个组分中标记的胸腺嘧啶核苷掺入脱氧核糖核酸(DNA)的量在6周龄动物中最高。在12周龄和15周龄动物中摄取量显著降低,在22周龄大鼠中最低。

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The effect of age on deoxyribonucleic acid synthesis in rat adipose tissue.年龄对大鼠脂肪组织中脱氧核糖核酸合成的影响。
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