Marder S R
VISN 22 Mental Illness Research, Education, and Clinical Center, the West Los Angeles Veterans Affairs Medical Center, CA 90073, USA.
Acta Psychiatr Scand Suppl. 2000(407):87-90. doi: 10.1034/j.1600-0447.2000.00017.x.
The objective of this study was to develop principles of combining pharmacological and psychosocial treatment that can be useful for clinicians who are treating patients with schizophrenia.
Research studies in schizophrenia that controlled both pharmacological and psychosocial treatments were reviewed. These included studies using conventional and newer antipsychotics as well as a number of psychosocial methods.
The interactions between the forms of treatment appear to be more than merely additive, since each can enhance the effects of the other. Drug and psychosocial treatments may affect different outcome domains, with the former affecting symptoms and the later affecting social outcomes. Recent studies using newer antipsychotics suggest that these agents improve the participation of patients in psychosocial treatments.
Understanding the interactions between psychosocial and pharmacological treatments can be useful for clinicians who are developing treatment strategies for patients with schizophrenia. Newer agents with different side-effect profiles and broader effectiveness appear to have improved the outcomes of psychosocial treatments.
本研究的目的是制定药理学与心理社会治疗相结合的原则，这对治疗精神分裂症患者的临床医生可能有用。
回顾了对药理学和心理社会治疗均进行控制的精神分裂症研究。这些研究包括使用传统和新型抗精神病药物以及多种心理社会方法的研究。
治疗形式之间的相互作用似乎不仅仅是累加的，因为每种治疗都可以增强另一种治疗的效果。药物治疗和心理社会治疗可能会影响不同的结果领域，前者影响症状，后者影响社会结果。最近使用新型抗精神病药物的研究表明，这些药物可提高患者参与心理社会治疗的程度。
了解心理社会治疗与药物治疗之间的相互作用对为精神分裂症患者制定治疗策略的临床医生可能有用。具有不同副作用特征和更广泛疗效的新型药物似乎改善了心理社会治疗的结果。
