Janssen-Cilag Pharmaceutical, Lisbon, Portugal.
Ann Gen Psychiatry. 2011 Jun 24;10:18. doi: 10.1186/1744-859X-10-18.
Schizophrenia is among the most disabling of mental illnesses and frequently causes impaired functioning. We explore issues of definition and terminology, and the relationship between social functioning, cognition, and psychopathology considering relevant research findings.
The present article describes measures of social functioning and outlines their psychometric properties. It considers their usefulness in research and clinical settings. Treatment aims and objectives are explored in the context of cognitive and social functioning. Finally, we identify areas for developing research and refining the measurement of social functioning.
The definition and measurement of social functioning in schizophrenia remains a complex and disputed area. The relationships between symptoms, cognitive functioning and social functioning are complex but we are beginning to understand them better. Scales for measuring functioning in clinical practice must be brief and sensitive to change and the Personal and Social Performance (PSP) scale may offer several advantages in these regards. Brief cognitive assessments focusing upon the domains most commonly affected in schizophrenia, such as verbal memory and executive functions, should be coadministered with measures of functioning.
The use of validated scales for schizophrenia that are sensitive to change over the course of the illness and its treatment, should allow for a better understanding of patients' functional disabilities, enabling better and more comprehensive monitoring and evaluation of both pharmacological and non-pharmacological treatment strategies.
精神分裂症是最具致残性的精神疾病之一,常导致功能受损。我们探讨了定义和术语问题,以及社会功能、认知和精神病理学之间的关系,同时考虑了相关的研究发现。
本文描述了社会功能的测量方法,并概述了它们的心理计量学特性。考虑了它们在研究和临床环境中的有用性。在认知和社会功能的背景下探讨了治疗目标。最后,我们确定了发展研究和完善社会功能测量的领域。
精神分裂症的社会功能定义和测量仍然是一个复杂和有争议的领域。症状、认知功能和社会功能之间的关系很复杂,但我们开始更好地理解它们。用于临床实践的功能测量量表必须简短且对变化敏感,个人和社会表现(PSP)量表在这些方面可能具有优势。简短的认知评估集中在精神分裂症最常受影响的领域,如言语记忆和执行功能,应与功能测量同时进行。
使用对疾病及其治疗过程中的变化敏感的经过验证的精神分裂症量表,可以更好地了解患者的功能障碍,从而更好地监测和评估药物和非药物治疗策略。