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[太原市正常及骨折女性胫骨骨含量与骨折阈值的定量超声测量]

[Measurement of tibia bone content and fracture threshold by quantitative ultrasonography in normal and fractured women in Taiyuan].

作者信息

Dong J, Zhang Z, Guo S

机构信息

First Clinic College, Shanxi Medical University, Taiyuan 030001.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1999 Feb;34(2):71-3.

PMID:11263200
Abstract

OBJECTIVE

To establish the reference range of tibia bone content in normal female of Taiyuan area and to explore the diagnostic criterion for osteoporotic fracture threshold by quantitative ultrasonography (QUS).

METHODS

The tibia bone contents (QUS value) of 1,681 normal women (aged 7-92 years) and 63 fractured women (aged 46-91) in Taiyuan were measured by QUS.

RESULTS

The QUS value increased with age in normal women before age 30, and peaked at age 30-40, then decreased and reached significance after age 50. There was a negative correlation between QUS value and duration after menopause (P < 0.01). Taken the mean QUS value of normal female aged 20-40 years minus 2.5 s (3,667 m/s) as a cutoff threshold, 93.7% of the 63 fractured women had their QUS value below this threshold.

CONCLUSION

It is suggested that the above cutoff QUS value may be considered as the risk threshold of osteoporotic fracture in women.

摘要

目的

建立太原地区正常女性胫骨骨量参考范围,探讨定量超声(QUS)诊断骨质疏松性骨折阈值的标准。

方法

采用QUS测量1681例年龄在7 - 92岁的正常女性和63例年龄在46 - 91岁的骨折女性的胫骨骨量(QUS值)。

结果

正常女性30岁之前QUS值随年龄增加,在30 - 40岁达到峰值,随后下降,50岁之后差异有统计学意义。QUS值与绝经后年限呈负相关(P < 0.01)。以20 - 40岁正常女性QUS值的平均值减去2.5标准差(3667米/秒)作为截断阈值,63例骨折女性中有93.7%的QUS值低于该阈值。

结论

建议上述QUS截断值可作为女性骨质疏松性骨折的风险阈值。

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