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加味玉屏风汤对截肢诱导应激状态下小鼠细胞免疫的调节作用

The regulatory action of the modified Yu Ping Feng Tang on cellular immunity in mice under amputation-induced stress.

作者信息

Chen X, Yang L, Zeng G, Shen G

机构信息

Shenzhen Red Cross Hospital, Shenzhen 518029.

出版信息

J Tradit Chin Med. 2000 Dec;20(4):302-6.

Abstract

To approach the action of modified Yu Ping Feng Tang ([symbol: see text] Jade-Screen Decoction) on cellular immunity, an experiment was conducted in mice under amputation-induced stress. On the 3rd day after amputation, acute atrophy was found in the thymus, the reactivities of T- and B-lymphocytes to Con-A and LPS were decreased, the IL-2 content and its activity reduced and the activity of NK cells lowered. The high, moderate and low concentrations of the modified Yu Ping Feng (YPF) Decoction all have antagonistic action on the above manifestations of immune inhibition.

摘要

为探讨玉屏风散加味方对细胞免疫的作用,在小鼠截肢致应激状态下进行了实验。截肢后第3天,发现胸腺急性萎缩,T淋巴细胞和B淋巴细胞对刀豆蛋白A(Con - A)和脂多糖(LPS)的反应性降低,白细胞介素 - 2(IL - 2)含量及其活性降低,自然杀伤细胞(NK细胞)活性降低。玉屏风散加味方的高、中、低浓度对上述免疫抑制表现均有拮抗作用。

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