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Comparative quantitation of immunoglobulin G (IgG) in cerebrospinal fluid and serum of children.

作者信息

Harms D

出版信息

Eur Neurol. 1975;13(1):54-64. doi: 10.1159/000114662.

DOI:10.1159/000114662
PMID:1126347
Abstract

Report on quantitation of IgG in cerebrospinal fluid (CSF) and serum of 84 children at different ages. A relation was shown between the content of IgG in CSF and serum depending on age. The decrease of the ratio CSF-IgG/serum-IgG as well as of the total protein in the CSF during the first trimenon points out a post-partal impediment of the diffusion from the blood to the CSF compartment. Beyond the first year of life the ratio of the concentrations mostly remains constant. Measurements in 135 children suffering from several neurological diseases showed that quantitation of IgG is of value only in case of suspicion of encephalitis with local synthesis of IgG.

摘要

相似文献

1
Comparative quantitation of immunoglobulin G (IgG) in cerebrospinal fluid and serum of children.
Eur Neurol. 1975;13(1):54-64. doi: 10.1159/000114662.
2
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[The pattern of cerebrospinal fluid proteins in infants and children. Determination of normal values (author's transl)].[婴幼儿脑脊液蛋白质的模式。正常值的测定（作者译）]
Arch Fr Pediatr. 1981 Jan;38(1):3-9.
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Concentrations of CSF proteins as a measure of blood brain barrier function and synthesis of IgG within the CNS in 'normal' subjects from the age of 6 months to 30 years.脑脊液蛋白浓度作为6个月至30岁“正常”受试者血脑屏障功能及中枢神经系统内IgG合成的一项指标。
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IgG subclasses, barrier function for albumin and production of immunoglobulin G in the central nervous system.免疫球蛋白G亚类、白蛋白的屏障功能及中枢神经系统中免疫球蛋白G的产生。
Acta Neurol Scand. 1979 Sep;60(3):129-39. doi: 10.1111/j.1600-0404.1979.tb02960.x.
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[Cerebrospinal fluid protein levels and blood-cerebrospinal fluid ratio of glucose and electrolytes in infants and children].[婴幼儿脑脊液蛋白质水平及脑脊液与血液中葡萄糖和电解质的比值]
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Principles of albumin and IgG analyses in neurological disorders. II. Relation of the concentration of the proteins in serum and cerebrospinal fluid.神经系统疾病中白蛋白和免疫球蛋白分析的原理。II. 血清和脑脊液中蛋白质浓度的关系。
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Flow rate of cerebrospinal fluid (CSF)--a concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases.脑脊液（CSF）流速——这是正常血脑屏障功能以及神经疾病功能障碍中都存在的一个共同概念。
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Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values.神经系统疾病中白蛋白和免疫球蛋白G分析的原则。I. 参考值的确定。
Scand J Clin Lab Invest. 1977 Sep;37(5):385-90. doi: 10.1080/00365517709091496.

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