Rajalakshmi M, Prasad M R
Fertil Steril. 1975 Feb;26(2):137-43. doi: 10.1016/s0015-0282(16)40933-7.
The effects of cyproterone acetate on the accessory organs of immature, prepubertal, and sexually mature adult rats were studied. Administration of CA to immature 30-day-old rats for 15 days markedly decreased the silaic acid in the caput and cauda epididymides and decreased the secretory activity of the accessory glands. Treatment of adult rats with CA for 15 days caused an increased incorporation of 3H-uridine into RNA and of 3H-phenylalanine into protein in the caput and cauda epididymides. The percentage of increase in the specific activity of RNA and protein was higher in the cauda epididymidis than in the caput epididymidis.
研究了醋酸环丙孕酮对未成熟、青春期前和性成熟成年大鼠附属器官的影响。给30日龄未成熟大鼠连续15天给予醋酸环丙孕酮，显著降低了附睾头和附睾尾中的唾液酸，并降低了附属腺的分泌活性。给成年大鼠连续15天给予醋酸环丙孕酮，导致附睾头和附睾尾中3H-尿苷掺入RNA以及3H-苯丙氨酸掺入蛋白质的量增加。附睾尾中RNA和蛋白质比活性的增加百分比高于附睾头。
