醋酸环丙孕酮对雄性大鼠睾丸及附属生殖器官的影响。
Effect of cyproterone acetate on testis and accessory sex organs of male rat.
作者信息
Kalla N R, Bhasin M
出版信息
Acta Eur Fertil. 1983 Nov-Dec;14(6):415-20.
PMID:6232808
Abstract
A significant reduction in testis, epididymis, seminal vesicles, prostate, and adrenal weight of adult rats was observed after CA treatment (10 mg/animal/day) for 13, 26 and 39 days. Biochemical assay on the epididymis showed a fall in the activities of acid and alkaline phosphatase. A significant fall in citric acid content of seminal vesicle and prostate in experimental animals was noted after CA treatment. Histoarchitecture of accessory sex organs was severely impaired.
摘要
在给予成年大鼠CA（10毫克/动物/天）治疗13、26和39天后，观察到其睾丸、附睾、精囊、前列腺和肾上腺重量显著减轻。对附睾进行的生化分析显示，酸性和碱性磷酸酶的活性下降。CA治疗后，实验动物精囊和前列腺中的柠檬酸含量显著下降。附属生殖器官的组织结构严重受损。
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