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[早期乳腺癌保乳手术及放疗后发生的乳腺血管肉瘤。病例报告]

[Angiosarcoma of the breast after conservative surgery and radiotherapy for early breast carcinoma. Description of a case].

作者信息

Griffa B, Basilico V, Clerici D, Bellotti R, Scognamiglio G, Zanardo M, Capriata G

机构信息

I Divisione di Chirurgia, Ospedale Valduce.

出版信息

Minerva Chir. 2000 Nov;55(11):799-802.

Abstract

The occurrence of an angiosarcoma of the residual breast after conservative surgery and adjuvant radiotherapy for early mammary carcinoma is a very rare event. In western countries only 57 cases have been published in the literature (5 in Italy) since the first described case in 1987. Radiotherapy seems to be the most important etiological factor in the development of the neoplasm. Diagnosis is often delayed, owing to the "benign" aspect of the lesion. The only effective treatment is residual mastectomy, because chemotherapy is ineffective. The prognosis is often dismal, because of the aggressive behaviour of the lesion in most cases. The case of a patient with a multicentric secondary angiosarcoma of the breast recently operated on is described.

摘要

早期乳腺癌保乳手术及辅助放疗后残留乳腺发生血管肉瘤是极为罕见的事件。自1987年首例报道以来,西方国家文献中仅发表了57例(意大利5例)。放疗似乎是该肿瘤发生的最重要病因。由于病变呈“良性”表现,诊断往往延迟。唯一有效的治疗方法是残余乳腺切除术,因为化疗无效。由于大多数情况下病变具有侵袭性,预后通常很差。本文描述了一名近期接受手术的多中心继发性乳腺血管肉瘤患者的病例。

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