Zabaleta M, García Cano F J, Preciado J A, Lacosta J L
Hospital San Millán, Logroño, La Rioja.
An Otorrinolaringol Ibero Am. 2001;28(1):87-99.
The extramedullary plasmacytoma account for 1-2% of the total number of plasma-cell growths. 80 percent are originated on head and neck, beginning on submucous layer of the upper airways. Male are more frequent affected at sixth-seventh decade. Roentgentherapy chemotherapy is only worldwide accepted in cases of scattered disease, but when the cases are localizated the method is under assessment. Long tern follow up of patients is recommended, because there are cases which after many years of calm can evolve into a multiple myeloma. We report 5 cases: 3 women and 2 men, diagnosed as extramedullary plasmocytoma. In one of them, considered as nasal plasmacytoma, three years later was discovered an other plasmacytoma on a tibial epiphysis. The whole group was surgically treated with complementary röntgentherapy 4 of them. Afterwards no one showed multiple myeloma.
髓外浆细胞瘤占浆细胞肿瘤总数的1% - 2%。80%起源于头颈部,始于上呼吸道黏膜下层。男性在六七十岁时更易患病。放射治疗化疗仅在疾病散在分布的情况下被全球认可,但当病例局限时,该方法仍在评估中。建议对患者进行长期随访,因为有些病例在多年平静后可能会发展为多发性骨髓瘤。我们报告5例:3名女性和2名男性,诊断为髓外浆细胞瘤。其中1例被认为是鼻浆细胞瘤,三年后在胫骨骨骺发现了另一个浆细胞瘤。整个组均接受了手术治疗,其中4例辅以放射治疗。此后无人出现多发性骨髓瘤。