MMWR Morb Mortal Wkly Rep. 2000 Jan 7;48(51-52):1165-7.
Staphylococcus aureus is one of the most common causes of hospital- and community-acquired infections. Nosocomial methicillin-resistant S. aureus (MRSA) infections have become common, and cases of community-acquired MRSA infections also have occurred. Since 1996, vancomycin-intermediate S. aureus (VISA; vancomycin minimum inhibitory concentration [MIC = 8-16 microg/mL) has been identified in Europe, Asia, and the United States. The emergence of reduced vancomycin susceptibility in S. aureus increases the possibility that some strains will become fully resistant and that available antimicrobial agents will become ineffective for treating infections caused by such strains. This report describes the fourth case of confirmed VISA from a patient in the United States.
金黄色葡萄球菌是医院获得性感染和社区获得性感染最常见的病因之一。医院内耐甲氧西林金黄色葡萄球菌（MRSA）感染已很常见，社区获得性MRSA感染病例也有发生。自1996年以来，在欧洲、亚洲和美国已发现万古霉素中介金黄色葡萄球菌（VISA；万古霉素最低抑菌浓度[MIC]=8 - 16微克/毫升）。金黄色葡萄球菌对万古霉素敏感性降低的出现增加了某些菌株完全耐药以及现有抗菌药物对治疗由此类菌株引起的感染变得无效的可能性。本报告描述了美国一名患者确诊的第四例VISA病例。
