MMWR Morb Mortal Wkly Rep. 1997 Jul 11;46(27):624-6.
Staphylococcus aureus is a virulent microorganism responsible for many serious infections among the general population. Since recognition of vancomycin-resistant enterococci (VRE), the emergence of vancomycin resistance in S. aureus has been anticipated. This report describes the first documented case of infection caused by S. aureus with reduced susceptibility to vancomycin and includes the initial characterization of this isolate (1); the case occurred in a pediatric patient in Japan. The emergence of reduced vancomycin susceptibility in S. aureus increases the possibility that some strains will become fully resistant and that currently available antimicrobial agents will become ineffective for treating infections caused by such strains.
金黄色葡萄球菌是一种致病性微生物，可导致普通人群中许多严重感染。自从认识到耐万古霉素肠球菌（VRE）以来，人们一直预计金黄色葡萄球菌会出现万古霉素耐药性。本报告描述了首例有记录的由对万古霉素敏感性降低的金黄色葡萄球菌引起的感染病例，并包括该分离株的初步特征描述（1）；该病例发生在日本的一名儿科患者身上。金黄色葡萄球菌对万古霉素敏感性降低的出现增加了一些菌株将完全耐药以及目前可用的抗菌药物对治疗由此类菌株引起的感染变得无效的可能性。
