Price P
Department of Cancer Therapeutics, ICSM Academic, Department of Radiation Oncology, Christie Hospital, Manchester, England.
Hepatogastroenterology. 2001 Jan-Feb;48(37):51-2.
Cholangiocarcinoma is a rare tumor. Many cases are localized while metastatic disease within the liver and abdomen do occur. There is as yet no standard therapy for advanced bile duct tumors. Radiotherapy and chemotherapy are not curative modalities in this condition but are being assessed adjuvantly following surgery, and as palliative treatment in an attempt to either extend progression-free and overall survival or to palliate symptoms. Advances may be made by: (i) The combined use of radiation and chemotherapy, (ii) High dose conformal radiotherapy, (iii) Novel chemotherapeutic agents. Patients should be given the opportunity to participate in clinical trials.
胆管癌是一种罕见的肿瘤。许多病例为局限性，但肝内和腹腔内的转移性疾病确实会发生。对于晚期胆管肿瘤，目前尚无标准治疗方法。放疗和化疗在此种情况下并非根治性手段，但正在评估其在手术后作为辅助治疗以及作为姑息治疗的效果，以期延长无进展生存期和总生存期或缓解症状。可通过以下方式取得进展：（i）放疗与化疗联合使用，（ii）高剂量适形放疗，（iii）新型化疗药物。应给予患者参与临床试验的机会。
