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脑内有单个囊肿的神经囊尾蚴病病例,在根治性手术切除后1年内特异性抗体滴度急剧下降。

Neurocysticercosis case with a single cyst in the brain showing dramatic drop in specific antibody titers within 1 year after curative surgical resection.

作者信息

Ito A, Nakao M, Ito Y, Yuzawa I, Morishima H, Kawano N, Fujii K

机构信息

Department of Parasitology, Asahikawa Medical College, Japan.

出版信息

Parasitol Int. 1999 Mar;48(1):95-9. doi: 10.1016/s1383-5769(99)00005-7.

DOI:10.1016/s1383-5769(99)00005-7
PMID:11269331
Abstract

We report on one Japanese case subject with neurocysticercosis (NCC) who had a single cyst in the brain and had undergone curative surgical resection. Pathological examination revealed that it was a cysticercus of Taenia solium. Serological examination of the pair serum samples just before and 1 year after surgery revealed that antibody responses against the glycoproteins, highly specific to NCC and detected in the serum sample just before surgery by both immunoblot and ELISA became negative within 1 year after the surgery. It is, therefore, strongly suggested that this case had a single cysticercus in his whole body and the presence of a single cysticercus was sufficient to evoke antibody responses against it.

摘要

我们报告了一例患有神经囊尾蚴病(NCC)的日本患者,其脑部有一个囊肿,并接受了根治性手术切除。病理检查显示为猪带绦虫囊尾蚴。手术前和手术后1年的配对血清样本血清学检查显示,针对糖蛋白的抗体反应,这些糖蛋白对NCC具有高度特异性,术前血清样本通过免疫印迹和ELISA均检测到,术后1年内变为阴性。因此,强烈提示该病例全身仅有一个囊尾蚴,且单个囊尾蚴的存在足以引发针对它的抗体反应。

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