Boussat S, El'rini T, Dubiez A, Depierre A, Barale F, Capellier G
Service de Réanimation Médicale, H pital J. Minjoz, Besançon, France.
Intensive Care Med. 2000 Dec;26(12):1811-6. doi: 10.1007/s001340000701.
To assess the lung cancer patient's prognosis in the intensive care unit with early predictive factors of death.
Retrospective study from July 1986 to February 1996.
Medical intensive care unit at a university hospital.
Fifty-seven patients with primary lung cancer admitted to our medical intensive care unit (MICU).
Data collection included demographic data (age, sex, underlying diseases, MICU admitting diagnosis) and evaluation of tumor (pathologic subtypes, metastases, lung cancer staging, treatment options). Three indexes were calculated for each patient: Karnofsky performance status, Simplified Acute Physiology Score (SAPS) II, and multisystem organ failure score (ODIN score). Mortality was high in the MICU: 66% of patients died during their MICU stay, and hospital mortality reached 75%. In multivariate analysis, acute pulmonary disease and Karnofsky performance status < 70 were associated with a poor MICU and post-MICU prognosis. For the survivors, long-term survival after MICU discharge depended exclusively on the severity of the lung cancer.
We confirmed the high mortality rate of lung cancer patients admitted to the MICU. Two predictive factors of death in MICU were identified: performance status < 70 and acute pulmonary disease.
通过死亡的早期预测因素评估重症监护病房中肺癌患者的预后。
1986年7月至1996年2月的回顾性研究。
一所大学医院的内科重症监护病房。
57例原发性肺癌患者入住我们的内科重症监护病房（MICU）。
数据收集包括人口统计学数据（年龄、性别、基础疾病、MICU入院诊断）和肿瘤评估（病理亚型、转移情况、肺癌分期、治疗方案）。为每位患者计算三个指标：卡氏功能状态评分、简化急性生理学评分（SAPS）II和多系统器官衰竭评分（ODIN评分）。MICU的死亡率很高：66%的患者在MICU住院期间死亡，医院死亡率达到75%。多因素分析显示，急性肺部疾病和卡氏功能状态评分<70与MICU及MICU后的不良预后相关。对于幸存者，MICU出院后的长期生存完全取决于肺癌的严重程度。
我们证实了入住MICU的肺癌患者死亡率很高。确定了MICU中两个死亡预测因素：功能状态评分<70和急性肺部疾病。
