Grist N R
J Clin Pathol. 1975 Apr;28(4):255-9. doi: 10.1136/jcp.28.4.255.
In a survey of laboratories where members of the Association of Clinical Pathologists worked, hepatitis was reported from 5 percent of 244 in 1970, 7 percent of 215 in 1971, and 2 percent of 337 in 1972. Of the 36 laboratories reporting hepatitis, a modest excess tested specimens from haemodialysis, transplant, and haemophilia units and performed tests for HB Ag. The average annual attack rate for staff of all types was 111 per 100,000 with higher rates for biochemists (268 in science graduates and 204 in technicians) and medical haematologists (258). Tests for HB Ag were positive in 17 cases ans negative in 15; nine were untested. No case was fatal and only 10 of the 41 required admission to hospital. Fourteen had a history of contract with 'high-risk (haemodialysis) specimens' but the most frequently suspected source of infection was personal contact with jaundiced or HB Ag-positive individuals and only in three cases were laboratory accidents suggested as the suspected source of infection. The findings indicate a need for caution and sensible safety precautions but not for exaggerated alarm.
在一项针对临床病理学家协会成员工作的实验室的调查中，1970年，244个实验室中有5%报告发生了肝炎；1971年，215个实验室中有7%报告发生了肝炎；1972年，337个实验室中有2%报告发生了肝炎。在报告肝炎的36个实验室中，适度过量检测了来自血液透析、移植和血友病单位的标本，并进行了乙肝表面抗原检测。所有类型工作人员的年平均发病率为每10万人111例，生物化学家（理科毕业生中为268例，技术人员中为204例）和血液学医生（258例）的发病率更高。乙肝表面抗原检测17例呈阳性，15例呈阴性；9例未检测。无一例死亡，41例中只有10例需要住院治疗。14例有接触“高风险（血液透析）标本”的病史，但最常被怀疑的感染源是与黄疸或乙肝表面抗原阳性个体的个人接触，只有3例怀疑感染源是实验室事故。研究结果表明需要谨慎并采取合理的安全预防措施，但无需过度恐慌。
