Verrill D, Barton C, Beasley W, Brennan M, Lippard M, King C
Northeast Medical Center Clinical Ressearch Institute, Concord, NC, USA.
J Cardiopulm Rehabil. 2001 Jan-Feb;21(1):37-46. doi: 10.1097/00008483-200101000-00008.
Quality of life (QOL) is an important health-related outcome measure in patients with cardiovascular disease. The North Carolina Cardiopulmonary Rehabilitation Association (NCCRA) is a coalition of 72 state-certified, multidisciplinary cardiac rehabilitation (CR) programs. In 1997, the NCCRA Executive Board and Research Committee agreed to collect ongoing data to assess QOL changes following CR participation using the Ferrans & Powers QOL Index Cardiac Version III. The purpose of this study was to determine if changes were present in QOL scores after 12 weeks of CR in men and women from multiple outpatient centers.
Data were analyzed from 420 patients from 19 Phase II early outpatient CR programs who completed the QOL index survey within the first week of program entry and upon discharge. The four QOL index domains measured were health/function, psychological/spiritual status, socioeconomic status, and family interaction. Overall QOL was tabulated as the aggregate score from the four domains. Each domain, as well as overall QOL, was compared pre- and post-CR participation with a repeated measures analysis of variance.
Across programs, statistically significant improvements in QOL indices were observed following 12 weeks of CR in each of the four domains and on the overall score in all patients. Men reported greater CR entry and discharge scores than women on the health/function, family interaction, and overall scores. Women showed a greater positive change in scores than men on the socioeconomic, family interaction, and overall scores.
Patients who participated in Phase II multidisciplinary North Carolina CR programs and completed the protocol improved QOL parameters. While men had higher physical function and overall QOL scores both pre- and post-CR, women showed greater improvements in overall scores, as well as in family and socioeconomic parameters. These findings suggest that North Carolina CR patients experience a positive change in QOL following short-term participation in CR. Further study with a larger number of patients benchmarked with programs from other regions with comparisons to patients who do not participate in formalized CR programs is indicated from this investigation.
生活质量(QOL)是心血管疾病患者重要的健康相关结局指标。北卡罗来纳心肺康复协会(NCCRA)是一个由72个州认证的多学科心脏康复(CR)项目组成的联盟。1997年,NCCRA执行委员会和研究委员会同意收集持续数据,以使用费兰斯和鲍尔斯生活质量指数心脏版III评估参与CR后的生活质量变化。本研究的目的是确定来自多个门诊中心的男性和女性在进行12周CR后生活质量评分是否有变化。
分析了来自19个II期早期门诊CR项目的420名患者的数据,这些患者在项目开始的第一周内以及出院时完成了生活质量指数调查。测量的四个生活质量指数领域为健康/功能、心理/精神状态、社会经济状况和家庭互动。总体生活质量以四个领域的总分表示。每个领域以及总体生活质量在参与CR前后通过重复测量方差分析进行比较。
在所有项目中,所有患者在四个领域中的每一个以及总体评分在进行12周CR后,生活质量指数均有统计学上的显著改善。在健康/功能、家庭互动和总体评分方面,男性报告的CR入院和出院评分高于女性。在社会经济、家庭互动和总体评分方面,女性的评分变化比男性更积极。
参与北卡罗来纳II期多学科CR项目并完成方案的患者改善了生活质量参数。虽然男性在CR前后的身体功能和总体生活质量评分都较高,但女性在总体评分以及家庭和社会经济参数方面有更大的改善。这些发现表明,北卡罗来纳的CR患者在短期参与CR后生活质量有积极变化。这项调查表明,需要对更多患者进行进一步研究,并与其他地区的项目进行基准比较,同时与未参与正规CR项目的患者进行比较。