单纯疱疹病毒1型通过角膜移植传播。
Herpes simplex virus 1 transmission through corneal transplantation.
作者信息
Remeijer L, Maertzdorf J, Doornenbal P, Verjans G M, Osterhaus A D
出版信息
Lancet. 2001 Feb 10;357(9254):442. doi: 10.1016/S0140-6736(00)04011-3.
Abstract
Genetic characterisation of herpes simplex virus type 1 (HSV-1) DNA isolated from a donor cornea before and after corneal transplantation demonstrated the transmission of HSV-1 through transplantation. This study is the first to provide conclusive evidence for the transmission of HSV-1 by penetrating keratoplasty with subsequent reactivation of donor-derived HSV-1 in the transplanted cornea.
摘要
对从供体角膜移植前后分离出的单纯疱疹病毒1型（HSV-1）DNA进行基因特征分析，证实了HSV-1通过移植传播。本研究首次提供确凿证据，证明穿透性角膜移植可传播HSV-1，并使移植角膜中供体来源的HSV-1随后重新激活。
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